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1,202 Result(s)
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Article
Open AccessSearch for the \( {B}_s^0 \) → μ+μ−γ decay
A search for the fully reconstructed B s 0 ...
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Open AccessMining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application.
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
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Open AccessR2-ISS staging combined with circulating plasma cells improves risk stratification for newly diagnosed multiple myeloma: a single-center real-world study
We aimed to evaluate if circulating plasma cells (CPC) detected by flow cytometry could add prognostic value of R2-ISS staging. We collected the electronic medical records of 336 newly diagnosed MM patients (N...
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Open AccessAssociation of elevated circulating monocyte-platelet aggregates with hypercoagulability in patients with nephrotic syndrome
Hypercoagulability emerges as a central pathological feature and clinical complication in nephrotic syndrome. Increased platelet activation and aggregability are closely related to hypercoagulability in nephro...
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Open AccessRole of liver sinusoidal endothelial cell in metabolic dysfunction-associated fatty liver disease
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells that represent the interface between blood cells on one side and hepatocytes on the other side. LSECs not only form a barrier...
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Open AccessSearch for central exclusive production of top quark pairs in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with tagged protons
A search for the central exclusive production of top quark-antiquark pairs ( t t ...
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Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
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Open AccessCorrection to: Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2V617F-induced myeloproliferative neoplasms
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Open AccessLINC00525 enhances ZNF460-regulated CD24 expression through the sponge miR-125a-5p to promote malignant progression of breast cancer
CD24 is a highly glycosylated glycosylphosphatidylinositol anchored membrane protein that plays an important role in tumor progression. The aim of this study was to investigate the effect of abnormal expressio...
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Open AccessClinical efficacy and prognostic factors of CT-guided radioactive iodine-125 seed implantation for the treatment of superficial soft tissue metastasis: a 12-year retrospective analysis
Superficial soft tissue metastasis (S-STM) of malignant tumors is uncommon and often brings great pain to patients. However, current treatment options are limited. The purpose of this study was to explore the ...
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Open AccessIdentification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
A growing body of evidence has highlighted the interactions of lipids metabolism and immune regulation. Nevertheless, there is still a lack of evidence regarding the causality between lipids and autoimmune dis...
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Open AccessCamrelizumab-based induction chemoimmunotherapy in locally advanced stage hypopharyngeal carcinoma: phase II clinical trial
This phase II trial aimed to determine the efficacy and safety of induction chemoimmunotherapy of camrelizumab plus modified TPF in locally advanced hypopharyngeal squamous cell carcinoma (LA HSCC) (NCT0415669...
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Open AccessWeChat assisted electronic symptom measurement for patients with adenomyosis
Symptom assessment is central to appropriate adenomyosis management. Using a WeChat mini-program-based portal, we aimed to establish a valid symptom assessment scale of adenomyosis (AM-SAS) to precisely and ti...
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Open AccessPyrotinib and trastuzumab plus palbociclib and fulvestrant in HR+/HER2+ breast cancer patients with brain metastasis
Human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) patients are at a high risk of develo** metastases in the brain. However, research focusing on treatment strategies for hormonal r...
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Open AccessA Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023
In recent years, spatial transcriptomics (ST) research has become a popular field of study and has shown great potential in medicine. However, there are few bibliometric analyses in this field. Thus, in this s...
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Open AccessMetabolism of alcohol ethoxylates (AEs) in rat, hamster, and human hepatocytes and liver S9: a pilot study for metabolic stability, metabolic pathway, and metabolites identification in vitro and in silico
Alcohol ethoxylates (AEs) are a well-known class of non-ionic surfactants widely used by the personal care market. The aim of this study was to evaluate and characterize the in vitro metabolism of AEs and iden...
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Open AccessAssociation between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018
Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulatio...
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Open AccessSearch for a new resonance decaying into two spin-0 bosons in a final state with two photons and two bottom quarks in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for a new boson X is presented using CERN LHC proton-proton collision data collected by the CMS experiment at ...
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Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...