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Article
Study on the spatial and temporal evolutionary characteristics of ozone concentration and the impact of human activities in China in 2019
Ozone (O3) pollution has a profound impact on human health, vegetation development, and the ecological environment, making it a critical focus of global academic research. In recent years, O3 pollution in China h...
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Article
Finite-Time Stability for Interval Type-2 Fuzzy Nonlinear Systems via an Observer-Based Sliding Mode Control
This work focuses on the design of a sliding mode controller for a class of continuous-time interval type-2 fuzzy-model-based nonlinear systems with unmeasurable state information over a finite-time interval. ...
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Article
Modeling Water Accessibility of Natural River Networks Using the Fine-Grained Physical Watershed Characteristics at the Grid Scale
Traditional assessments of water resources use water availability as an evaluating metric. Water availability is a statistical average and cannot reflect the spatial differences of water resources in a region ...
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Article
Open AccessKnockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells
Magnesium is essential for numerous physiological functions. Magnesium exists mostly in bone and the amount is dynamically regulated by skeletal remodeling. Accelerating bone mass loss occurs when magnesium in...
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Article
Open AccessGlucocorticoid receptor and Histone deacetylase 6 mediate the differential effect of dexamethasone during osteogenesis of mesenchymal stromal cells (MSCs)
Lineage commitment and differentiation of mesenchymal stromal cells (MSCs) into osteoblasts in vitro is enhanced by a potent synthetic form of glucocorticoid (GC), dexamethasone (Dex). Paradoxically, when used ch...
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Article
Open AccessBio- chemical and physical characterizations of mesenchymal stromal cells along the time course of directed differentiation
Cellular biophysical properties are novel biomarkers of cell phenotypes which may reflect the status of differentiating stem cells. Accurate characterizations of cellular biophysical properties, in conjunction...
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Article
Open AccessMechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through Osterix pathway
Microenvironments that modulate fate commitments of mesenchymal stromal cells (MSCs) are composed of chemical and physical cues, but the latter ones are much less investigated. Here we demonstrate that intermi...
