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    Article

    Anthracycline-containing regimens or taxane versus S-1 as first-line chemotherapy for metastatic breast cancer

    We have previously demonstrated S-1 is non-inferior to taxane with respect to overall survival as first-line chemotherapy for HER2-negative metastatic breast cancer. We aimed to confirm whether S-1 is also non...

    Hirofumi Mukai, Yukari Uemura, Hiromitsu Akabane in British Journal of Cancer (2021)

  2. Article

    Open Access

    Ki-67 response-guided preoperative chemotherapy for HER2-positive breast cancer: results of a randomised Phase 2 study

    The effectiveness of a therapeutic strategy that switches chemotherapy, based on Ki-67 tumour expression after initial therapy, relative to that of standard chemotherapy, has not been evaluated.

    Hirofumi Mukai, Takeshi Yamaguchi, Masato Takahashi in British Journal of Cancer (2020)

  3. Article

    Open Access

    Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer

    Fusion genes are good candidates of molecular targets for cancer therapy. However, there is insufficient research on the clinical implications and functional characteristics of fusion genes in colorectal cance...

    Yuri Choi, Chae Hwa Kwon, Seon ** Lee, Joonghoon Park in British Journal of Cancer (2018)