6 Result(s)

Article

Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3β/β-catenin signaling pathways

Sulforaphane is a common antioxidant selectively abundant in cruciferous plants, which exhibits effective anti-cancer actions in control of tumorigenesis or progression of various cancers. A recent study has s...

Da-xuan Wang, Yu-jiao Zou, **-bin Zhuang, Shu-xing Chen… in Acta Pharmacologica Sinica (2017)

Article

ROS activates JNK-mediated autophagy to counteract apoptosis in mouse mesenchymal stem cells in vitro

Transplantation of mesenchymal stem cells (MSCs) for the treatment of diabetic erectile dysfunction (ED) is hampered by apoptosis of the transplanted cells. In diabetic ED, there is increased oxidative stress ...

Guan-yu Liu, **ao-xue Jiang, **n Zhu, Wei-yang He… in Acta Pharmacologica Sinica (2015)

Article

Comment on: Incidence and Risk of Hypertension with Ramucirumab in Cancer Patients: A Meta-Analysis of Published Studies

Andreas Sashegyi, Yong Lin, David Ferry, Allen Melemed in Clinical Drug Investigation (2015)

Article

Crocetin induces cytotoxicity and enhances vincristine-induced cancer cell death via p53-dependent and -independent mechanisms

To investigate the anticancer effect of crocetin, a major ingredient in saffron, and its underlying mechanisms.

Ying-jia Zhong, Fang Shi, Xue-lian Zheng, Qiong Wang… in Acta Pharmacologica Sinica (2011)

Article

Tumor necrosis factor and cancer, buddies or foes?

Tumor necrosis factor (TNF) is a multifunctional cytokine that plays important roles in diverse cellular events such as cell survival, proliferation, differentiation, and death. As a pro-inflammatory cytokine,...

**a Wang, Yong Lin in Acta Pharmacologica Sinica (2008)