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Article
Open AccessUsing a longitudinal network structure to subgroup depressive symptoms among adolescents
Network modeling has been proposed as an effective approach to examine complex associations among antecedents, mediators and symptoms. This study aimed to investigate whether the severity of depressive symptom...
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Article
Open AccessPrevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase
Neuraminidase (NA) of human influenza H3N2 virus has evolved rapidly and been accumulating mutations for more than half-century. However, biophysical constraints that govern the evolutionary trajectories of NA...
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Article
Open AccessHedgehog signaling controls mouth opening in the amphioxus
The left-sided position of the mouth in amphioxus larvae has fascinated researchers for a long time. Despite the fundamental importance of mouth development in the amphioxus, the molecular regulation of its de...
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Article
Open AccessPitx controls amphioxus asymmetric morphogenesis by promoting left-side development and repressing right-side formation
Left-right (LR) asymmetry is an essential feature of bilateral animals. Studies in vertebrates show that LR asymmetry formation comprises three major steps: symmetry breaking, asymmetric gene expression, and L...
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Article
Open AccessSequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
Since the COVID-19 pandemic onset, the antibody response to SARS-CoV-2 has been extensively characterized. Antibodies to the receptor binding domain (RBD) on the spike protein are frequently encoded by IGHV3-5...
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Article
Open AccessA psychometric investigation of the Chinese version of the Internal, Personal and Situational Attributions Questionnaire (C-IPSAQ)
The IPSAQ is a self-administered instrument designed to evaluate individuals’ attributional style (AS). The purpose of this study is to examine the psychometric properties of the Chinese version of the Interna...
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Article
Open AccessEvolutionary history of the extant amphioxus lineage with shallow-branching diversification
Amphioxus or lancelets have been regarded as a key animal in understanding the origin of vertebrates. However, the evolutionary history within this lineage remains unexplored. As the amphioxus lineage has like...
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Article
Open AccessDecelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes
Vertebrates diverged from other chordates ~500 Myr ago and experienced successful innovations and adaptations, but the genomic basis underlying vertebrate origins are not fully understood. Here we suggest, thr...
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Article
Open AccessProteomic characterization and evolutionary analyses of zona pellucida domain-containing proteins in the egg coat of the cephalochordate, Branchiostoma belcheri
Zona pellucida domain-containing proteins (ZP proteins) have been identified as the principle constituents of the egg coat (EC) of diverse metazoan taxa, including jawed vertebrates, urochordates and molluscs ...
