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  1. Article

    Open Access

    RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma

    The failure of melanoma immunotherapy can be mediated by immunosuppression in the tumor microenvironment (TME), and insufficient activation of effector T cells against the tumor. Here, we show that inhibition ...

    Yanan Guo, Rong Shen, Keren Yang, Yutong Wang, Haoyun Song… in Cell Death Discovery (2023)

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    Article

    DNA Damage-Induced Foci of E2 Ubiquitin-Conjugating Enzyme are Detectable upon Co-transfection with an Interacting E3 Ubiquitin Ligase

    DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conv...

    Degui Wang, Yingxia Tian, Dong Wei, Yuhong **g, Haitao Niu… in Biochemical Genetics (2016)

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    Article

    IGF-1 gene-modified muscle-derived stem cells are resistant to oxidative stress via enhanced activation of IGF-1R/PI3K/AKT signaling and secretion of VEGF

    Reactive oxygen species (ROS)-induced oxidative stress increases in skeletal muscle with aging and decreases the viability of implanted cells. Type 1 insulin-like growth factor (IGF-1) promotes the survival of...

    Chun**g Chen, Ying Xu, Yanfeng Song in Molecular and Cellular Biochemistry (2014)

  4. No Access

    Article

    The assessment of voluntary pelvic floor muscle contraction by three-dimensional transperineal ultrasonography

    The assessment of the levator function by ultrasound has not been fully studied. This study aims to test the validity of ultrasound parameters in the assessment of levator function in women presenting with dif...

    Ruiyun Chen, Yanfeng Song, Li Jiang, **nru Hong… in Archives of Gynecology and Obstetrics (2011)

  5. No Access

    Article

    Prospective randomized trial of TVT and TOT as primary treatment for female stress urinary incontinence with or without pelvic organ prolapse in Southeast China

    To compare the outcomes of tension- free vaginal tape (TVT) and transobturator tape (TOT) in the treatment of female stress urinary incontinence with or without concomitant pelvic organ prolapse (POP).

    Fengmei Wang, Yanfeng Song, Huijuan Huang in Archives of Gynecology and Obstetrics (2010)

  6. No Access

    Article

    Which placement of the tension-free vaginal tape is more important for urinary continence: midurethral position or bladder neck? Consideration from a case report

    The tension-free vaginal tape (TVT) is a well-established surgical procedure for the treatment of female urinary stress incontinence. Midurethral position was thought not to be necessary to achieve continence....

    Fengmei Wang, Yanfeng Song, Huijuan Huang in International Urogynecology Journal (2009)

  7. No Access

    Article

    Role of vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide in the vaginal wall of women with stress urinary incontinence and pelvic organ prolapse

    Pelvic floor connective tissue degeneration is closely associated with retrogradation of its dominating nerve fibers. We hypothesized that some neuropeptides from pelvic floor tissue might be involved in the p...

    **nru Hong, Lili Huang, Yanfeng Song in International Urogynecology Journal (2008)

  8. No Access

    Article

    Changes of collagen type III and decorin in paraurethral connective tissue from women with stress urinary incontinence and prolapse

    Thirteen premenopausal women with stress urinary incontinence (SUI), 6 with SUI and prolapse, 9 with prolapse, and 19 without prolapse were enrolled to observe the content change of collagen type III and the e...

    Yanfeng Song, **nru Hong, Yan Yu, Yibin Lin in International Urogynecology Journal (2007)

  9. No Access

    Article

    Biomechanical properties of prolapsed vaginal tissue in pre- and postmenopausal women

    The aim of this study was to explore the relationship between biomechanical properties and the occurrence of pelvic organ prolapse (POP) through analysis on biomechanical properties of vaginal tissue. The biop...

    Lingling Lei, Yanfeng Song, RiQi Chen in International Urogynecology Journal (2007)