56 Result(s)

Article

Efficacy and safety of bispecific antibodies vs. immune checkpoint blockade combination therapy in cancer: a real-world comparison

Emerging tumor immunotherapy methods encompass bispecific antibodies (BSABs), immune checkpoint inhibitors (ICIs), and adoptive cell immunotherapy. BSABs belong to the antibody family that can specifically rec...

Linyan Cheng, Lujun Chen, Yuan Shi, Weiying Gu, Weidong Ding… in Molecular Cancer (2024)

Article

A nomogram for predicting adverse pathologic features in low-risk papillary thyroid microcarcinoma

Identifying risk factors for adverse pathologic features in low-risk papillary thyroid microcarcinoma (PTMC) can provide valuable insights into the necessity of surgical or non-surgical treatment. This study a...

Lei Gong, ** Li, **g**g Liu, Yan Liu, **nghong Guo, Weili Liang, Bin Lv… in BMC Cancer (2024)

Article

Construction and validation of a nomogram to predict the overall survival of small cell lung cancer: a multicenter retrospective study in Shandong province, China

Patients diagnosed with small cell lung cancer (SCLC) typically experience a poor prognosis, and it is essential to predict overall survival (OS) and stratify patients based on distinct prognostic risks.

Ziqian Song, Hengmin Ma, Hao Sun, Qiuxia Li, Yan Liu, **g **e, Yukun Feng… in BMC Cancer (2023)

Article

Analysis of m7G-Related signatures in the tumour immune microenvironment and identification of clinical prognostic regulators in breast cancer

Breast cancer is a malignant tumour that seriously threatens women’s life and health and exhibits high inter-individual heterogeneity, emphasising the need for more in-depth research on its pathogenesis. While...

Qinghua Huang, Jianlan Mo, Huawei Yang, Yinan Ji, Rong Huang, Yan Liu… in BMC Cancer (2023)

Article

Clinical relevance of pathogenic germline variants in mismatch repair genes in Chinese breast cancer patients

The prevalence and clinical relevance of pathogenic germline variants in MMR genes have not been investigated in large series of breast cancers. In this study, we screened the germline variants in MMR genes in...

Li Hu, Jie Sun, Zhongwu Li, Ziwei Qu, Yan Liu, Qiting Wan, Jiaming Liu… in npj Breast Cancer (2022)

Article

The HIF1α-PDGFD-PDGFRα axis controls glioblastoma growth at normoxia/mild-hypoxia and confers sensitivity to targeted therapy by echinomycin

Glioblastoma multiforme (GBM), a lethal brain tumor, remains the most daunting challenge in cancer therapy. Overexpression and constitutive activation of PDGFs and PDGFRα are observed in most GBM; however, ava...

Gong Peng, Yin Wang, Pengfei Ge… in Journal of Experimental & Clinical Cancer … (2021)

Article

Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Early diagnosis can significantly improve treatment outcomes for hepatocellular carcinoma (HCC) patients. Currently, the dosage of serum alpha fetoprotein (AFP) is widely used in the diagnosis of HCC, but this...

Jian Zhou, Yue Zhu, Yi Li, Kun Liu, Fei He, Sihuan Xu… in Infectious Agents and Cancer (2021)

Article

Correction to: Exosomes derived from gemcitabine resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p

An amendment to this paper has been published and can be accessed via the original article.

Feng Wei, Chengyuan Ma, Tong Zhou, Xuechao Dong, Qinghua Luo, Li Geng… in Molecular Cancer (2021)

Article

Epidemiological, Clinical and Serological Characteristics of Children with Coronavirus Disease 2019 in Wuhan: A Single-centered, Retrospective Study

Dan Luo, Zhi **a, Heng Li, Danna Tu, Ting Wang, Wei Zhang, Lu Peng… in Virologica Sinica (2020)

Article

An evaluation of solid versus liquid transport media for high-risk HPV detection and cervical cancer screening on self-collected specimens

The solid transport media is a small size card that allows fast, easy DNA extraction from a variety of biological samples. In 2016 we developed a solid media transport card; for that pilot study to control the...

Hui Du, **anzhi Duan, Yan Liu, Bin Shi, Wei Zhang… in Infectious Agents and Cancer (2020)

Article

Evaluation of an isothermal amplification HPV detection assay for primary cervical cancer screening

The aim of this research was to evaluate independently the performance of a new isothermal amplification assay for cervical cancer screening compared to two previously validated PCR-based assays and histologic...

Wei Zhang, Hui Du, **a Huang, Chun Wang, **anzhi Duan… in Infectious Agents and Cancer (2020)

Article

USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer

Triple-negative breast cancer (TNBC), in part because of the high metastasis rate, is one of the most prevalent causes of malignancy-related mortality globally. Ubiquitin specific peptidase 6 N-terminal like (...

Teng Ma, Huaidong Liu, Yan Liu, Tingting Liu, Hui Wang, Fulu Qiao, Lu Song… in BMC Cancer (2020)

Article

Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model

Zika virus (ZIKV) is emerging as a significant pathogen worldwide and may cause severe neurological disorders such as fetal microcephaly and Guillain-Barre syndrome. No drug or listed vaccines are currently av...

Dan Luo, Yuanjiu Miao, **anliang Ke, Zhongyuan Tan, Chun Hu… in Virologica Sinica (2020)