10 Result(s)
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Article
Yamile Marquez
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Evolution of tissue-specific expression of ancestral genes across vertebrates and insects
Regulation of gene expression is arguably the main mechanism underlying the phenotypic diversity of tissues within and between species. Here we assembled an extensive transcriptomic dataset covering 8 tissues ...
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Open AccessA high-resolution single-molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis
Accurate and comprehensive annotation of transcript sequences is essential for transcript quantification and differential gene and transcript expression analysis. Single-molecule long-read sequencing technolog...
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Open AccessExOrthist: a tool to infer exon orthologies at any evolutionary distance
Several bioinformatic tools have been developed for genome-wide identification of orthologous and paralogous genes. However, no corresponding tool allows the detection of exon homology relationships. Here, we ...
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Open AccessPublisher Correction: Conservative route to genome compaction in a miniature annelid
A Correction to this paper has been published: https://doi.org/10.1038/s41559-020-01327-6.
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Open AccessConservative route to genome compaction in a miniature annelid
The causes and consequences of genome reduction in animals are unclear because our understanding of this process mostly relies on lineages with often exceptionally high rates of evolution. Here, we decode the ...
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Open AccessAlternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals
Alternative splicing (AS) is a widespread regulatory mechanism in multicellular organisms. Numerous transcriptomic and single-gene studies in plants have investigated AS in response to specific conditions, esp...
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A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons
The mechanisms by which entire programmes of gene regulation emerged during evolution are poorly understood. Neuronal microexons represent the most conserved class of alternative splicing in vertebrates, and a...
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Open AccessAmphioxus functional genomics and the origins of vertebrate gene regulation
Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications. Here we sequence the genome of the Mediterranea...
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Open AccessEvolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes
Epithelial-mesenchymal interactions are crucial for the development of numerous animal structures. Thus, unraveling how molecular tools are recruited in different lineages to control interplays between these t...
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Open AccessNodulin 41, a novel late nodulin of common bean with peptidase activity
The legume-rhizobium symbiosis requires the formation of root nodules, specialized organs where the nitrogen fixation process takes place. Nodule development is accompanied by the induction of specific plant g...
