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Article
De-Training Effects Following Leucine-Enriched Whey Protein Supplementation and Resistance Training in Older Adults with Sarcopenia: A Randomized Controlled Trial with 24 Weeks of Follow-Up
This study aimed to evaluate the effectiveness of de-training after a combined intervention of leucine-enriched whey protein supplementation and resistance training on skeletal muscle mass and strength in olde...
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Article
Open AccessESICM LIVES 2016: part two
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Article
Open AccessEffectiveness of early ureteric stenting for urosepsis associated with urinary tract calculi
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Article
Open AccessAnalysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality
It has been a challenge to determine breast cancer clonality accurately. The aim of the present study was to assess methods using formalin-fixed paraffin-embedded (FFPE) tissue to differentiate new primary tum...
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Article
Cation off-stoichiometric SrMnO3−δ thin film grown by pulsed laser deposition
The laser energy density (laser fluence) dependency of the Sr/Mn ratio was investigated for SrMnO3−δ (SMO) thin films grown by pulsed laser deposition (PLD). It was found that the Sr/Mn ratio showed a steep incre...
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Article
Characterization of Deep Levels in 3C-SiC by Optical-Capacitance-Transient Spectroscopy
An optical-capacitance-transient spectroscopy (O-CTS) method was used to characterize the defects in 3C-SiC on Si. The O-CTS measurement enables us to estimate optical threshold energy and optical cross sectio...
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Article
Open AccessLapatinib monotherapy in patients with relapsed, advanced, or metastatic breast cancer: efficacy, safety, and biomarker results from Japanese patients phase II studies
HER2-positive metastatic breast cancer (MBC) relapsing after trastuzumab-based therapy may require continued HER2 receptor inhibition to control the disease and preserve the patients' quality-of-life. Efficacy...
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Article
What is full recovery? Reconsidering outcome of cardiopulmonary cerebral resuscitation beyond Glasgow–Pittsburgh Cerebral Performance Categories 1
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Open AccessOverexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome
The purpose of the present study is to identify genes that contribute to cell proliferation or differentiation of breast cancers independent of signalling through the oestrogen receptor (ER) or human epidermal...
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Article
Nasal Mask Bilevel Positive Airway Pressure Ventilation for Diaphragmatic Paralysis After Pediatric Open-Heart Surgery
A 2-year-old boy underwent surgical repair of tetralogy of Fallot. Topical cooling of the heart with ice slush was used during the operation. Diaphragmatic paralysis occurred after the operation, inducing seve...
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Article
Eclamptic encephalopathy: MRI, including diffusion-weighted images
Eclampsia is a rare condition peculiar to pregnant and puerperal women. We analyse imaging features in five patients with eclampsia, and determine whether diffusion-weighted imaging (DWI) could differentiate ...
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Article
Methicillin-Resistant Staphylococcus aureus Endocarditis Following Repair of Tetralogy of Fallot
Infectious endocarditis following cardiac surgery, particularly that caused by methicillin-resistant Staphylococcus, aureus is a rare and highly lethal complication. We report a case of a 2-year-old girl who d...
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Article
Effects of a structured psychiatric intervention on cancer patients' emotions and co** styles
Background. The aim of this study was to investigate the clinical effectiveness of a structured group intervention program for Japanese patients with breast cancer.
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Article
Management and outcome of symptomatic hyponatremia in emergency department
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Article
Bacterial versus viral meningitis: comparison of the old and the new clinical prediction models
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Article
Analgesic effects of sub-Tenon’s versus retrobulbar anesthesia in planned extracapsular cataract extraction
Background: A prospective study was conducted to compare the analgesic effects of sub-Tenon’s and retrobulbar anesthesia by assessing patients’ response to the visceral stimulus. Methods: Seven hundred and twent...
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Article
Open AccessDose escalation and pharmacokinetic study of a humanized anti-HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
We conducted a phase I pharmacokinetic dose escalation study of a recombinant humanized anti-p185HER2 monoclonal antibody (MKC-454) in 18 patients with metastatic breast cancer refractory to chemotherapy. Three o...
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Article
Physicians' perspectives on "do-not-resuscitate" (DNR) orders
Background. The purpose of this study was to investigate physicians' perspectives on do-not-resuscitate (DNR) orders at Tokai University hospital, where a euthanasia-like accident occurred several years ago.
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Article
High-dose chemotherapy with autologous hematopoietic stem-cell transplantation in breast cancer
Since 1981 we have conducted four studies of the treatment of metastatic and postoperative high-risk breast cancer with high-dose chemotherapy supported by autologous hematopoietic stem-cell transplantation (...
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Article
New immunodeficient (nude-scid, beige-scid) mice as excellent recipients of human skin grafts containing intraepidermal neoplasms
Engraftment of normal or lesional human skin onto nude or SCID (severe combined immunodeficiency) mice has been used as an in vivo experimental model. However, this model has some limitations, su...
