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  1. No Access

    Article

    Gastric intestinal metaplasia: progress and remaining challenges

    Most gastric cancers arise in the setting of chronic inflammation which alters gland organization, such that acid-pum** parietal cells are lost, and remaining cells undergo metaplastic change in differentiat...

    Qi-Yue Tong, Min-Jiao Pang, **ao-Hai Hu, Xuan-Zhang Huang in Journal of Gastroenterology (2024)

  2. Article

    Open Access

    Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis

    Peritoneal metastasis is the leading cause of death for gastrointestinal cancers. The native and therapy-induced ascites ecosystems are not fully understood. Here, we characterize single-cell transcriptomes of...

    Xuan-Zhang Huang, Min-Jiao Pang, Jia-Yi Li, Han-Yu Chen in Nature Communications (2023)

  3. Article

    Open Access

    Survival landscape of different tumor regression grades and pathologic complete response in rectal cancer after neoadjuvant therapy based on reconstructed individual patient data

    Neoadjuvant therapy can lead to different tumor regression grades (TRG) in rectal cancer after neoadjuvant therapy. The purposes of this study are to investigate the relationships among TRG, pathologic complet...

    Jia-yi Li, Xuan-zhang Huang, Peng Gao, Yong-xi Song, **ao-wan Chen in BMC Cancer (2021)

  4. Article

    Open Access

    Continuous Wound Infiltration with Local Anesthetic Is an Effective and Safe Postoperative Analgesic Strategy: A Meta-Analysis

    Postoperative pain management is an essential module for perioperative care, especially for enhanced recovery after surgery programs. Continuous wound infiltration (CWI) with local anesthetic may be a promisin...

    Xuan-zhang Huang, Jun-hua Zhao, Peng Gao, **ao-wan Chen, Yong-xi Song in Pain and Therapy (2021)

  5. Article

    Open Access

    Impact of timing of adjuvant chemotherapy on survival in stage III colon cancer: a population-based study

    There is no consensus regarding the optimal time to initiate adjuvant chemotherapy after surgery for stage III colon cancer, and the relevant postoperative complications that cause delays in adjuvant chemother...

    Peng Gao, Xuan-zhang Huang, Yong-xi Song, **g-xu Sun, **ao-wan Chen, Yu Sun in BMC Cancer (2018)

  6. No Access

    Article

    Meta-analysis of the laparoscopic versus open colorectal surgery within fast track surgery

    Laparoscopic methods and fast-track surgery (FTS) can enhance recovery and reduce postoperative hospital stay. However, whether laparoscopic surgery can provide short-term benefits within FTS is controversial....

    Jun-hua Zhao, **g-xu Sun, Xuan-zhang Huang in International Journal of Colorectal Disease (2016)

  7. No Access

    Article

    Laparoscopic resection with natural orifice specimen extraction versus conventional laparoscopy for colorectal disease: a meta-analysis

    We wished to determine the effects of laparoscopic resection using natural orifice specimen extraction (NOSE) for patients with colorectal disease through a meta-analysis.

    Bin Ma, Xuan-zhang Huang, Peng Gao in International Journal of Colorectal Disease (2015)

  8. No Access

    Article

    Aspirin and nonsteroidal anti-inflammatory drugs after but not before diagnosis are associated with improved breast cancer survival: a meta-analysis

    The association between nonsteroidal anti-inflammatory drugs (NSAIDs) and breast cancer survival is still controversial. The aim of our meta-analysis was to assess the survival benefit of NSAIDs.

    Xuan-zhang Huang, Peng Gao, **g-xu Sun, Yong-xi Song in Cancer Causes & Control (2015)

  9. Article

    Open Access

    Which is the best postoperative chemotherapy regimen in patients with rectal cancer after neoadjuvant therapy?

    There is no general agreement about whether patients who have already received neoadjuvant chemoradiotherapy need further postoperative chemotherapy based on 5-fluorouracil(5-FU) or 5-FU plus oxaliplatin.

    Peng Gao, Yong-xi Song, **g-xu Sun, **ao-wan Chen, Ying-ying Xu in BMC Cancer (2014)

  10. Article

    Open Access

    Fast-track surgery versus traditional perioperative care in laparoscopic colorectal cancer surgery: a meta-analysis

    Both laparoscopic and fast-track surgery (FTS) have shown some advantages in colorectal surgery. However, the effectiveness of using both methods together is unclear. We performed this meta-analysis to compare...

    Jun-hua Zhao, **g-xu Sun, Peng Gao, **ao-wan Chen, Yong-xi Song in BMC Cancer (2014)