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Open AccessProceedings of Réanimation 2017, the French Intensive Care Society International Congress
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Open AccessCase report: quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationships
Methadone, the most widely delivered maintenance therapy for heroin addicts, may be responsible for life-threatening poisonings with respiratory depression. The toxicokinetics and the toxicokinetic/toxicodynam...