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  1. Article

    Open Access

    Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR δ activation

    The blood-brain barrier (BBB) is pivotal for the maintenance of brain homeostasis and it strictly regulates the cerebral transport of a wide range of endogenous compounds and drugs. While fasting is increasing...

    Stéphanie Chasseigneaux, Véronique Cochois-Guégan… in Fluids and Barriers of the CNS (2024)

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  2. Article

    Open Access

    Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses

    Endothelial cells (ECs) are constantly submitted in vivo to hemodynamical forces derived from the blood circulation, including shear stress (SS). ECs are able to detect SS and consequently adapt their phenotyp...

    Nina Choublier, Meryam Taghi, Marie-Claude Menet… in Fluids and Barriers of the CNS (2022)

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  3. Article

    Open Access

    Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels

    AhR activates the transcription of several target genes including CYP1B1. Recently, we showed CYP1B1 as the major cytochrome P450 (CYP) enzyme expressed in human brain microvessels. Here, we studied the effect of...

    Aude Jacob, Anika MS Hartz, Sophie Potin, Xavier Coumoul… in Fluids and Barriers of the CNS (2011)

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