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A survey of the response of Korean medicinal plants on drug metabolism
Alcohol extracts of plants widely used in the traditional medicine have been tested to establish if they affect the metabolism of drugs in mice.
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Article
Sedative action of spinosin
The acute toxicity and the sedative action of spinosin isolated fromZizyphus seeds have been tested with mice.
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Article
Carbon-13 NMR spectra of phytolaccagenin and its glycosides
In connection with structure studies on triterpenoid glycosides fromPhytolacca plants, full assignments of13C-NMR signals of phytolaccagenin and its glycosides, phytolaccoside B and E, have been presented.
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Article
Biological evaluation of Korean medicinal plants(III)
The extracts of sixty Korean plants were evaluated for their biological activities such as antitumor activities against Sarcoma 180, Leukemia SN-36 and Ehrlich ascites carcinoma, antimicrobial activities and b...
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A further survey of the action of some medicinal plants on drug metabolism
Tabulated results are presented of a test for an activity affecting on drug metabolism of 75 plant samples frequently used in the traditional medicine in Korea.
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Article
Central nervous depressant activity of piperine
Piperine showed a central nervous system depressant activity which was characterized by the antagonistic effect against chemoshock seizure as well as potent muscular incoordination in mice.
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A survey of the action of KoreanAngelica plants on drug metabolism
Eight species of the genusAngelica in Korea were examined for the activity of affecting drug metabolism and for the presence of coumarins. The results showed that various parts, especially roots and fruits ofAnge...
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Screening of Korean medicinal plants for antitumor activity
Potential antitumor activity of sixteen Korean medicinal plants was tested against leukemia SN 36, murine tumor model. Survival studies by measuring life span indicated thatMorus alba (Moraceae), Verbascum phlomo...
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Article
Effect of six Chinese drugs on serum transaminase activity and liver tissue in mice
The methanol extracts ofPatriniae radix,Dianthii herba,Melandrii herba,Echinopii radix,Siegesbeckiae herba andMagnoliae cortex showed a significant elevation of serum transaminase activity accompanied by fatty de...
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Article
3′,4′,7-trihydroxyflavone inAlbizzia julibrissin
From the stembark ofAlbizzia julibrissin. 3′, 4′, 7-trihydroxyflavone and α-spinasteryl-d-glucoside were isolated.
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Article
Acetonylidene americanin A, an artefact isolated fromPhytolacca americana
From the seeds ofPhytolacca americana, acetonylidene americanin A was isolated and its structure elucidated mainly by spectroscopic methods. This compound is not a genuine constitutent but formed in the tissue on...
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Article
A flavonoid glycoside from the leaves ofPolygonum sachalinense (II)
Quercetin-3-O-β-d-glucofuranoside, mp 243∼6°, was isolated from leaves ofPolygonum sachalinense Fr. Schm. and characterized on the basis of its spectral data. This is the second report of its occurrence in nature...
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Article
Isolation of a new sapogenin fromAlbizzia julibrissin
From the hydrolysate of the strong uterotonic active saponin ofAlbizzia julibrissin a new sapogenin, machaerinic acid methylester together with acacic acid lactone was isolated and characterized.
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Article
Sapogenins fromAlbizzia julibrissin
From the stem bark ofAlbizzia julibrissin (Leguminosae) two known sapogenins, acacigenin B, and machaerinic acid lactone, were isolated and identified by chemical and spectral data. It is the second time that the...
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Article
Phytochemical study onRandia siamensis
From the roots ofRandia siamensis,d-mannitol, a mixture of β-sitosterol and campesterol, oleanolic acid acetate, oleanolic acid-3-α-l-arabinoside and mesembryanthemoidigenic acid as a sapogenin were isolated and ...
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Article
Effect of spices on hepatic microsomal enzyme function in mice
The effect of twenty two spices on liver microsomal monooxygense activity was tested as measured by alteration of hexobarbital (HB) narcosis and strychnine mortality in mice. Oral administration of seven spice...
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Article
A sapogenin ofRandia siamensis
From the roots ofRandia siamensis (Rubiaceae), 3β, 30-dihydroxy-urs-12-en-Z8-oic acid (30-hydroxy ursolic acid) was isolated and characterized by spectral data.
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Article
Pharmacological study on piperine
Systematic pharmacological studies on piperine have revealed that this compound elicited diverse pharmacological activities; CNS depressant activity characterized by antagonism against electroshock seizure and...
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Article
Coumarins and triterpenoid glycosides from the roots ofPatrinia scabiosaefolia
From the roots ofPatrinia scabiosaefolia (Valerianaceae), scopoletin (1), esculetin (2), oleanonic acid (3), 3-O-α-l-rhamnopyranosyl(1→2)-α-l-arabinopyranosyl oleanolic acid (4) and 3-O-α-l-rhamnopyranosyl (1→2)-...
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Article
Antiinflammatory activity of americanin a
Americanin A from the seeds ofPhytolacca americana, was investigated for the antiinflammatory activity. The compound significantly inhibited edema induction, granuloma formation, arthritis induction and leucocyte...