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  1. Article

    Open Access

    The Aldose Reductase Inhibitor Epalrestat Maintains Blood–Brain Barrier Integrity by Enhancing Endothelial Cell Function during Cerebral Ischemia

    Excessive activation of aldose reductase (AR) in the brain is a risk factor for aggravating cerebral ischemia injury. Epalrestat is the only AR inhibitor with proven safety and efficacy, which is used in the c...

    Tongshuai Zhang, **rong Wu, **nmin Yao, Yao Zhang, Yue Wang in Molecular Neurobiology (2023)