10 Result(s)
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Article
Open AccessRole of mucus-bacteria interactions in Enterotoxigenic Escherichia coli (ETEC) H10407 virulence and interplay with human microbiome
The intestinal mucus layer has a dual role in human health constituting a well-known microbial niche that supports gut microbiota maintenance but also acting as a physical barrier against enteric pathogens. En...
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Open AccessSpatial and temporal modulation of enterotoxigenic E. coli H10407 pathogenesis and interplay with microbiota in human gut models
Enterotoxigenic Escherichia coli (ETEC) substantially contributes to the burden of diarrheal illnesses in develo** countries. With the use of complementary in vitro models of the human digestive environment, TN...
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Open AccessOral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile
Oral diseases (e.g., dental caries, periodontitis) are developed when the healthy oral microbiome is imbalanced allowing the increase of pathobiont strains. Common practice to prevent or treat such diseases is...
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Article
Open AccessShort-term supplementation of celecoxib-shifted butyrate production on a simulated model of the gut microbial ecosystem and ameliorated in vitro inflammation
Celecoxib has been effective in the prevention and treatment of chronic inflammatory disorders through inhibition of altered cyclooxygenase-2 (COX-2) pathways. Despite the benefits, continuous administration m...
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Article
Open AccessArabinoxylans, inulin and Lactobacillus reuteri 1063 repress the adherent-invasive Escherichia coli from mucus in a mucosa-comprising gut model
The microbiota that colonises the intestinal mucus may particularly affect human health given its proximity to the epithelium. For instance, the presence of the adherent-invasive Escherichia coli (AIEC) in this m...
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Open AccessMicromanagement in the gut: microenvironmental factors govern colon mucosal biofilm structure and functionality
The human gut microbiome provides us with functional features that we did not have to evolve ourselves and can be viewed as a structured microbial community that operates like a microbial organ within the huma...
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Improved in vitro assay for determining the mucin adherence of bacteria sensitive to Triton X-100 treatment
Mucin-associated microbiota are in relatively close contact with the intestinal epithelium and may thus have a more pronounced effect on host health. We have previously developed a simple mucin agar assay to s...
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Open AccessThe HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro
Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by th...
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Assessment of mutualism between Bombus terrestris and its microbiota by use of microcolonies
Social pollinators, like honeybees and bumblebees, have specific microbiota. The specific association between the insect and its gut microbiota could lead to a functional dependence. In this project, we invest...
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Article
Open AccessMicrobial community of predatory bugs of the genus Macrolophus(Hemiptera: Miridae)
The predatory mirids of the genus Macrolophus are key natural enemies of various economically important agricultural pests. Both M. caliginosus and M. pygmaeus are commercially available for the augmentative biol...
