6 Result(s)
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Article
Tatsuya Katsuno
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Article
Local coordination of epithelial planar polarity in the maintenance and regeneration of the adult rat airway
The maintenance of planar polarity in airway multiciliated cells (MCCs) has been poorly characterized. We recently reported that the direction of ciliary beating in a surgically inverted tracheal segment remai...
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Article
Open AccessFunctional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the develo** neural tube and cochlear sensory epithelium
Although the core constituents of the Wnt/planar cell polarity (PCP) signaling have been extensively studied, their downstream molecules and protein–protein interactions have not yet been fully elucidated. Her...
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Article
Open AccessA novel method for live imaging of human airway cilia using wheat germ agglutinin
Multiciliated epithelial cells in the airway are essential for mucociliary clearance. Their function relies on coordinated, metachronal and directional ciliary beating, appropriate mucus secretion and airway s...
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Open AccessCochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens
To protect the audiosensory organ from tissue damage from the immune system, the inner ear is separated from the circulating immune system by the blood-labyrinth barrier, which was previously considered an imm...
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Article
Open AccessDigenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome
Enlarged vestibular aqueduct (EVA) is one of the most commonly identified inner ear malformations in hearing loss patients including Pendred syndrome. While biallelic mutations of the SLC26A4 gene, encoding pendr...
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Article
Open AccessLong-term preservation of planar cell polarity in reversed tracheal epithelium
Planar cell polarity (PCP) coordinates the patterning and orientation of cells and their structures along tissue planes, and although its acquisition during the formation of airway epithelium has been describe...
