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    Article

    Indoxyl sulfate enhances IL-1β-induced E-selectin expression in endothelial cells in acute kidney injury by the ROS/MAPKs/NFκB/AP-1 pathway

    Uremic toxins are considered a risk factor for cardiovascular disorders in kidney diseases, but it is not known whether, under inflammatory conditions, they affect adhesion molecule expression on endothelial c...

    Wen-Ching Shen, Chan-Jung Liang, Tao-Ming Huang, Chen-Wei Liu… in Archives of Toxicology (2016)

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    Article

    In acute kidney injury, indoxyl sulfate impairs human endothelial progenitor cells: modulation by statin

    Renal ischemia rapidly mobilizes endothelial progenitor cells (EPCs), which provides renoprotection in acute kidney injury (AKI). Indoxyl sulfate (IS) is a protein-binding uremic toxin with a potential role in...

    Vin-Cent Wu, Guang-Huar Young, Po-Hsun Huang, Shyh-Chyi Lo, Kuo-Chuan Wang… in Angiogenesis (2013)