26 Result(s)

Article

MRI features and tumor-infiltrating CD8 + T cells-based nomogram for predicting meningioma recurrence risk

This study was based on MRI features and number of tumor-infiltrating CD8 + T cells in post-operative pathology, in predicting meningioma recurrence risk.

Tao Han, **anwang Liu, Changyou Long, Shenglin Li, Fengyu Zhou… in Cancer Imaging (2024)

Article

Correlation of bilateral M1 hand area excitability and overall functional recovery after spinal cord injury: protocol for a prospective cohort study

After spinal cord injury (SCI), a large number of survivors suffer from severe motor dysfunction (MD). Although the injury site is in the spinal cord, excitability significantly decreases in the primary motor ...

Chunqiu Dai, **aodong Lin, Baijie Xue, **ao **, Ming Gao, **nyu Liu… in BMC Neurology (2024)

Article

System analysis based on Anoikis-related genes identifies MAPK1 as a novel therapy target for osteosarcoma with neoadjuvant chemotherapy

Osteosarcoma (OS) is the most common bone malignant tumor in children, and its prognosis is often poor. Anoikis is a unique mode of cell death.However, the effects of Anoikis in OS remain unexplored.

Zhouwei Wu, Jiapei Yu, Tao Han, Yiting Tu, Fang Su, Shi Li… in BMC Musculoskeletal Disorders (2024)

Article

End-organ damage from neonatal invasive fungal infection: a 14-year retrospective study from a tertiary center in China

Invasive fungal infection (IFI) has become an increasing problem in NICU neonates, and end-organ damage (EOD) from IFI is one of the leading causes of morbidity and mortality in neonates. This study was conduc...

Tao Han, Meng Qiu, **nxin Niu, Shumei wang, Feng Wang… in BMC Infectious Diseases (2024)

Article

The Hippo-YAP signaling pathway drives CD24-mediated immune evasion in esophageal squamous cell carcinoma via macrophage phagocytosis

Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in the world with poor prognosis. Despite the promising applications of immunotherapy, the objective response rate is still unsa...

**aofeng Zhou, Ziyi Yan, **ghan Hou, Lichen Zhang, Zhen Chen, Can Gao… in Oncogene (2024)

Article

Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways

G-protein coupled receptors (GPCRs) are recognized as attractive targets for drug therapy. However, it remains poorly understood how GPCRs, except for a few chemokine receptors, regulate the progression of liv...

Kun Zhang, Meng-**a Zhang, **ao-**ang Meng, **g Zhu… in Military Medical Research (2023)

Article

Clinical features and prognosis of acute-on-chronic liver failure in patients with recompensated cirrhosis

There are few studies on acute-on-chronic liver failure (ACLF) in patients with recompensated cirrhosis. This study was aimed to investigate the clinical features of ACLF patients with recompensated cirrhosis.

Haixia Yuan, Yingying Cao, Zhenjun Yu, Yue Huang, Fang Liu… in BMC Gastroenterology (2023)

Article

Comparison of post-treatment recurrence between ranibizumab injection and laser photocoagulation for type 1 retinopathy of prematurity

To compare post-treatment recurrence between ranibizumab injection and laser photocoagulation (LP) for type 1 retinopathy of prematurity (ROP), and explore the associated risk factors.

**g-Ke Cao, Tao Han, Hong-Yi Tang, Sheng Zhang, Zong-Hua Wang… in BMC Ophthalmology (2023)

Article

Metformin regulates chondrocyte senescence and proliferation through microRNA-34a/SIRT1 pathway in osteoarthritis

Osteoarthritis (OA) is the most common degenerative disease in joints among elderly patients. Senescence is deeply involved in the pathogenesis of osteoarthritis. Metformin is widely used as the first-line dru...

Shiju Yan, Wen**g Dong, Zhirui Li… in Journal of Orthopaedic Surgery and Research (2023)

Article

Management and operation of extra-large Fangcang hospitals: experience and lessons from containing the highly contagious SARS-CoV-2 Omicron in Shanghai, China

Yun **an, Chenhao Yu, Minjie Chen, Lin Zhang, **nyi Zheng… in Frontiers of Medicine (2023)

Article

Clinical application of artificial liver and blood purification: expert consensus recommendations

Yu Chen, Tao Han, Zhong** Duan in Hepatology International (2023)

Article

Nomogram based on MRI can preoperatively predict brain invasion in meningioma

Predicting brain invasion preoperatively should help to guide surgical decision-making and aid the prediction of meningioma grading and prognosis. However, only a few imaging features have been identified to a...

**g Zhang, Yuntai Cao, Guo** Zhang, Zhiyong Zhao, Jianqing Sun… in Neurosurgical Review (2022)

Article

LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway

Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of human diseases. The dysregulation of liver sinusoidal endothelial cell (LSEC) phenotype is a critical early event in the fibro...

Ting Chen, Zhemin Shi, Yanmian Zhao, **aoxiang Meng, Sicong Zhao… in BMC Medicine (2022)

Article

Characteristics of acute kidney injury and its impact on outcome in patients with acute-on-chronic liver failure

Acute kidney injury (AKI) is a common and life-threatening complication of liver failure. The purpose of this study is to construct a nomogram and online calculator to predict the development of hospital-acqui...

Yue Huang, Junjun Cai, Fushuang Ha, Beichen Guo, … in BMC Gastroenterology (2022)

Article

HLF regulates ferroptosis, development and chemoresistance of triple-negative breast cancer by activating tumor cell-macrophage crosstalk

Tumor-associated macrophages (TAMs) are major components of the tumor microenvironment (TME) which are closely associated with the tumor malignant progression. However, the regulatory mechanisms by which TAMs ...

Hengyu Li, **hua Yang, **gHan Wang, ** Zhang… in Journal of Hematology & Oncology (2022)

Article

Hepatitis B-related acute-on-chronic liver failure induced by hepatotropic viral insult is associated with worse prognosis than that induced by non-virus insult

The manifestations and prognoses of acute-on-chronic liver failure (ACLF) with different precipitating events remain heterogeneous. We aimed to investigate the characteristics and prognosis of patients with he...

**g Liang, Lei Liu, Yingying Cao, Qian Zhang, Fang Liu, Yu Chen… in BMC Infectious Diseases (2021)

Article

Invasive Pulmonary Aspergillosis in Acute-on-Chronic Liver Failure Patients: Short-Term Outcomes and Antifungal Options

Acute-on-chronic liver failure (ACLF) patients are susceptible to invasive fungal infections. We evaluated the prognosis and antifungal options in ACLF patients with invasive pulmonary aspergillosis (IPA).

Danli Chen, Zhi** Qian, Haibin Su, Zhongji Meng… in Infectious Diseases and Therapy (2021)

Article

Tolvaptan therapy of Chinese cirrhotic patients with ascites after insufficient diuretic routine medication responses: a phase III clinical trial

To determine the safety and efficacy of different doses of tolvaptan for treating Chinese cirrhotic patients with or without hyponatraemia who still had ascites after routine therapy with diuretics.

Jieting Tang, Yongfeng Wang, Tao Han, Qing Mao, Jun Cheng… in BMC Gastroenterology (2020)

Article

Optimized real-time fluorescence PCR assay for the detection of porcine Circovirus type 3 (PCV3)

Porcine circovirus type 3 (PCV3) has been an emerging porcine virus spread around the world. The conserved DNA sequence of PCV3 enabled good performance in molecular biological assays.

Lin Yuan, Yingyi Liu, Yana Chen, **aoxue Gu, Hao Dong… in BMC Veterinary Research (2020)

Article

Analysis of the pharmacological mechanism of Banxia **exin decoction in treating depression and ulcerative colitis based on a biological network module

The network pharmacology method was used to predict the active components of Banxia **exin decoction, its targets and the key signalling pathways that are activated in the treatment of depression and ulcerativ...

Ying Yu, Gong Zhang, Tao Han, Hailiang Huang in BMC Complementary Medicine and Therapies (2020)