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  1. Article

    Open Access

    System analysis based on Anoikis-related genes identifies MAPK1 as a novel therapy target for osteosarcoma with neoadjuvant chemotherapy

    Osteosarcoma (OS) is the most common bone malignant tumor in children, and its prognosis is often poor. Anoikis is a unique mode of cell death.However, the effects of Anoikis in OS remain unexplored.

    Zhouwei Wu, Jiapei Yu, Tao Han, Yiting Tu, Fang Su, Shi Li in BMC Musculoskeletal Disorders (2024)

  2. Article

    Open Access

    End-organ damage from neonatal invasive fungal infection: a 14-year retrospective study from a tertiary center in China

    Invasive fungal infection (IFI) has become an increasing problem in NICU neonates, and end-organ damage (EOD) from IFI is one of the leading causes of morbidity and mortality in neonates. This study was conduc...

    Tao Han, Meng Qiu, **nxin Niu, Shumei wang, Feng Wang in BMC Infectious Diseases (2024)

  3. Article

    Open Access

    The Hippo-YAP signaling pathway drives CD24-mediated immune evasion in esophageal squamous cell carcinoma via macrophage phagocytosis

    Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in the world with poor prognosis. Despite the promising applications of immunotherapy, the objective response rate is still unsa...

    **aofeng Zhou, Ziyi Yan, **ghan Hou, Lichen Zhang, Zhen Chen, Can Gao in Oncogene (2024)

  4. No Access

    Article

    The value of an apparent diffusion coefficient histogram model in predicting meningioma recurrence

    To investigate the predictive value of a model combining conventional MRI features and apparent diffusion coefficient (ADC) histogram parameters for meningioma recurrence.

    Tao Han, **anwang Liu, Mengyuan **g in Journal of Cancer Research and Clinical On… (2023)

  5. Article

    Open Access

    Clinical features and prognosis of acute-on-chronic liver failure in patients with recompensated cirrhosis

    There are few studies on acute-on-chronic liver failure (ACLF) in patients with recompensated cirrhosis. This study was aimed to investigate the clinical features of ACLF patients with recompensated cirrhosis.

    Haixia Yuan, Yingying Cao, Zhenjun Yu, Yue Huang, Fang Liu in BMC Gastroenterology (2023)

  6. Article

    Open Access

    Characteristics of acute kidney injury and its impact on outcome in patients with acute-on-chronic liver failure

    Acute kidney injury (AKI) is a common and life-threatening complication of liver failure. The purpose of this study is to construct a nomogram and online calculator to predict the development of hospital-acqui...

    Yue Huang, Junjun Cai, Fushuang Ha, Beichen Guo, in BMC Gastroenterology (2022)

  7. Article

    Open Access

    Hepatitis B-related acute-on-chronic liver failure induced by hepatotropic viral insult is associated with worse prognosis than that induced by non-virus insult

    The manifestations and prognoses of acute-on-chronic liver failure (ACLF) with different precipitating events remain heterogeneous. We aimed to investigate the characteristics and prognosis of patients with he...

    **g Liang, Lei Liu, Yingying Cao, Qian Zhang, Fang Liu, Yu Chen in BMC Infectious Diseases (2021)

  8. Article

    Open Access

    Invasive Pulmonary Aspergillosis in Acute-on-Chronic Liver Failure Patients: Short-Term Outcomes and Antifungal Options

    Acute-on-chronic liver failure (ACLF) patients are susceptible to invasive fungal infections. We evaluated the prognosis and antifungal options in ACLF patients with invasive pulmonary aspergillosis (IPA).

    Danli Chen, Zhi** Qian, Haibin Su, Zhongji Meng in Infectious Diseases and Therapy (2021)

  9. Article

    Open Access

    Tolvaptan therapy of Chinese cirrhotic patients with ascites after insufficient diuretic routine medication responses: a phase III clinical trial

    To determine the safety and efficacy of different doses of tolvaptan for treating Chinese cirrhotic patients with or without hyponatraemia who still had ascites after routine therapy with diuretics.

    Jieting Tang, Yongfeng Wang, Tao Han, Qing Mao, Jun Cheng in BMC Gastroenterology (2020)

  10. Article

    Open Access

    Analysis of the pharmacological mechanism of Banxia **exin decoction in treating depression and ulcerative colitis based on a biological network module

    The network pharmacology method was used to predict the active components of Banxia **exin decoction, its targets and the key signalling pathways that are activated in the treatment of depression and ulcerativ...

    Ying Yu, Gong Zhang, Tao Han, Hailiang Huang in BMC Complementary Medicine and Therapies (2020)

  11. Article

    Open Access

    Liver cirrhosis in a patient with hepatic hereditary hemorrhagic telangiectasia and Budd–Chiari syndrome: a case report

    Hereditary hemorrhagic telangiectasia (HHT) often involves the liver, and belongs to abnormal blood vessel disease. The etiology of Budd–Chiari syndrome (BCS) is not clear, but congenital vascular dysplasia is...

    Bai-Guo Xu, **g Liang, Ke-Feng Jia, Tao Han in BMC Gastroenterology (2020)

  12. Article

    Open Access

    A nationwide survey on neonatal medical resources in mainland China: current status and future challenges

    With the rapid development of economy in recent two decades, neonatology has been progressing quickly in China. However, there is little knowledge about the exact developmental status of neonatal departments i...

    Qiu** Li, Tao Han, Yan** Zhang, Qian Zhang, **angyong Kong in BMC Pediatrics (2019)

  13. Article

    Open Access

    Tolvaptan treatment improves survival of cirrhotic patients with ascites and hyponatremia

    Although tolvaptan treatment improves hyponatremia, only few studies have investigated whether tolvaptan actually benefits the survival of cirrhotic patients. This study evaluated the impact of tolvaptan on si...

    Shuzhen Wang, **n Zhang, Tao Han, Wen **e, Yonggang Li, Hong Ma in BMC Gastroenterology (2018)

  14. No Access

    Article

    MiR-345 suppresses proliferation, migration and invasion by targeting Smad1 in human prostate cancer

    The roles of dysregulated microRNAs in prostate cancer metastasis are still unknown. In this study, we found that the expression of miR-345 was significantly downregulated in prostate cancer and clinical prost...

    Qi-guang Chen, Wei Zhou, Tao Han, Shu-qi Du in Journal of Cancer Research and Clinical On… (2016)