![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin
The serine/threonine protein kinase Akt is involved in a variety of cellular processes including cell proliferation, survival, metabolism and gene expression. It is essential in vascular endothelial growth fac...
-
Article
All-optical analog-to-digital conversion system with a spatial coding method using designed filter
We propose and demonstrate an all-optical analog-to-digital conversion system with a spatial coding method using a designed filter. To make available codes more flexible, the design technique for a computer-ge...
-
Article
Impurity-Related Local Density-of-States Modulation in Bi2Sr2Ca(Cu1−x Zn x )2O8+δ Probed by Scanning Tunneling Spectroscopy
We have performed scanning tunneling spectroscopy on a single crystal of Bi2Sr2Ca(Cu1−x Zn x )2O8+δ (x=0.005) and found several r...
-
Article
Stapled resection for bronchogenic cyst of the esophagus performed using video-assisted thoracic surgery
Esophageal bronchogenic cyst is a rare congenital malformation. Although thoracoscopic resection is useful, it has not been adopted for esophageal cysts with a large size or severe inflammatory adhesions. We f...
-
Article
Open AccessThe Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility
Dishevelled is the common mediator of canonical and non-canonical Wnt signalling pathways, which are important for embryonic development, tissue maintenance and cancer progression. In the non-canonical Wnt sig...
-
Article
One-dimensional Electronic Order in Fe1.07Te Probed by Scanning Tunneling Spectroscopy
We have performed scanning tunneling microscopy on Fe1.07Te that is the parent compound of the iron-chalcogenide superconductors (SCs). The results indicate the existence of the unidirectional electronic order wi...
-
Article
Open AccessMetamorphosis of mesothelial cells with active horizontal motility in tissue culture
Mesothelial cells, which have diverse roles in physiology and pathology, constitute the mesothelium along with connective tissue and the basement membrane; the mesothelium serves to shield the somatic cavities...
-
Article
Significance of cancer-associated fibroblasts in the regulation of gene expression in the leading cells of invasive lung cancer
Cancer-associated fibroblasts (CAFs) contribute to tumor progression through multiple pathways. However, the effect of CAFs on gene expression in lung cancer has been largely unknown. Here we systematically co...
-
Article
Open AccessLow blood cell counts in wild Japanese monkeys after the Fukushima Daiichi nuclear disaster
In April 2012 we carried out a 1-year hematological study on a population of wild Japanese monkeys inhabiting the forest area of Fukushima City. This area is located 70 km from the Fukushima Daiichi Nuclear Po...
-
Article
Open AccessIdentification of Meflin as a Potential Marker for Mesenchymal Stromal Cells
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) in culture are derived from BM stromal cells or skeletal stem cells. Whereas MSCs have been exploited in clinical medicine, the identification of MSC-spe...
-
Article
A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion
Cancer-associated fibroblasts (CAFs) promote tumour invasion and metastasis. We show that CAFs exert a physical force on cancer cells that enables their collective invasion. Force transmission is mediated by a...
-
Article
Open AccessSmall head size and delayed body weight growth in wild Japanese monkey fetuses after the Fukushima Daiichi nuclear disaster
To evaluate the biological effect of the Fukushima Daiichi nuclear disaster, relative differences in the growth of wild Japanese monkeys (Macaca fuscata) were measured before and after the disaster of 2011 in Fuk...
-
Article
Open AccessThe Number of Louse Eggs on Wild Japanese Macaques (Macaca fuscata) Varies with Age, but Not with Sex or Season
During grooming, primates remove harmful ectoparasites, such as ticks and lice, and there is direct evidence for a health benefit of tick removal. Grooming behaviors differ among primates with respect to age a...
-
Article
Open AccessPharmacokinetics of a Single Dose of Azilsartan in Pediatric Patients: A Phase 3, Open-Label, Multicenter Study
Azilsartan is an angiotensin II receptor blocker indicated for the treatment of patients with hypertension. The efficacy and safety of azilsartan are established in adults, but have not been evaluated in pedia...
-
Article
Radius of curvature at the talocrural joint surface: inference of subject-specific kinematics
The coupled behavior of talocrural joint motion is primarily determined by the morphological features of the talar trochlea and tibiofibular mortise. Features of the radius of curvature of the talocrural joint...
-
Article
Effect of hip angle on neuromuscular activation of the adductor longus and adductor magnus muscles during isometric hip flexion and extension
Neuromuscular activation of the adductor longus (AL) and adductor magnus (AM) muscles at different hip flexion angles during hip flexion and extension has not been clarified. This study aimed to compare the re...
-
Article
Open AccessPossible transmission of Sarcoptes scabiei between herbivorous Japanese serows and omnivorous Caniformia in Japan: a cryptic transmission and persistence?
Two transmission patterns of Sarcoptes scabiei in host mammal communities have been reported based on microsatellite-level genetic studies in the last two decades. While one involves restrictions among different ...
-
Article
Alport–leiomyomatosis syndrome requiring subtotal esophagectomy for refractory gastroesophageal reflux disease after childhood partial esophagogastrectomy: a case report
Alport–leiomyomatosis syndrome is an extremely rare condition occurring at a young age in which Alport syndrome coexists with diffuse leiomyomatosis of the digestive tract (primarily the esophagus). Most patie...
-
Article
Open AccessConcentrations of 137Cs radiocaesium in the organs and tissues of low-dose-exposed wild Japanese monkeys
Following the massive earthquake that struck eastern Japan on March 11, 2011, a large amount of radioactive material was released into the environment from the damaged reactor of the Fukushima Daiichi Nuclear ...
-
Article
Open AccessIntestinal endometriosis treated by laparoscopic surgery: case series of 5 patients
Intestinal endometriosis is rare and most frequently involves the rectum and sigmoid colon.