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  1. No Access

    Article

    Phenotypic Evolution in Fabry Disease: Our Experience in Indian Cohort

    The current study aimed to explore phenotypic evolution in Fabry disease according to demographics, genotype, specific enzyme activity and pathogenicity scores. We integrated clinical, biochemical, and genomic...

    Usha Dave, Srilatha Kadali, Tajamul Hussain… in Indian Journal of Clinical Biochemistry (2024)

  2. No Access

    Article

    Structure-Based Virtual Screening, Molecular Docking, Molecular Dynamics Simulation of EGFR for the Clinical Treatment of Glioblastoma

    Glioblastoma (GBM) is a WHO Grade IV tumor with poor visibility, a high risk of comorbidity, and exhibit limited treatment options. Resurfacing from second-rate glioma was originally classified as either manda...

    Anushka Bhrdwaj, Mohnad Abdalla, Aditi Pande… in Applied Biochemistry and Biotechnology (2023)

  3. No Access

    Article

    Adaptive Neuro-Fuzzy Inference System-Based Exploration of the Interrelationships of 25-Hydroxyvitamin D, Calcium, Phosphorus with Parathyroid Hormone Production

    The rationale of the current study was to assess the prevalence of 25-hydroxyvitamin D (25-OHD) deficiency and hyperparathyroidism in South Indian population and to explore interrelationships of 25-OHD, Ca, P ...

    Iyyapu Krishna Mohan, Siraj Ahmed Khan… in Indian Journal of Clinical Biochemistry (2020)

  4. No Access

    Article

    Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes

    Obesity, genetic polymorphisms of xenobiotic metabolic pathway, hypermethylation of tumor suppressor genes, and hypomethylation of proapoptotic genes are known to be independent risk factors for breast cancer....

    Shaik Mohammad Naushad, Tajamul Hussain… in Molecular and Cellular Biochemistry (2014)

  5. No Access

    Article

    Induction of CYP1A1, CYP1A2, CYP1B1, increased oxidative stress and inflammation in the lung and liver tissues of rats exposed to incense smoke

    Incense smoke is increasingly being recognized as a potential environmental contaminant and is linked to malignant and non-malignant respiratory diseases. The detoxification of environmental contaminants inclu...

    Tajamul Hussain, Omar S. Al-Attas… in Molecular and Cellular Biochemistry (2014)

  6. No Access

    Article

    The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects

    Paraoxonase-1 (PON1) is a HDL-bound antioxidant enzyme that protects LDL from oxidative modification. Discovery of the antioxidant properties of PON1 led to extensive research on its role in the initiation and...

    Mohammed A. Hassan, Omar S. Al-Attas… in Molecular and Cellular Biochemistry (2013)

  7. No Access

    Article

    Poly A RNA status and expression of milli (m) and micro (μ) calpains in skeletal muscle of duchenne muscular dystrophy patients

    Poly A RNA status and itsin vitro translation in a rabbit reticulolysate cell free system, were assessed in the skeletal muscle of young boys with Duchenne muscular dystrophy. Compared to normals there is a signi...

    Harleen Mangat, Tajamul Hussain, C Sundaram… in Indian Journal of Clinical Biochemistry (2002)

  8. No Access

    Article

    Analysis of Bcl I and Xba I polymorphism in factor VIII gene to detect carriers of haemophilia a in Andhra Pradesh

    The efficacy of two intragenic polymorphic markers of factor VIII gene has been examined in Andhra Pradesh population with a view to confirm/revise the strategy for carrier detection that would be precise and ...

    P. Aruna Prabhavathi, Tajamul Hussain… in Indian Journal of Clinical Biochemistry (2002)

  9. No Access

    Article

    Quantitation of endogenous inhibitor of milli-CANP in Duchenne muscular dystrophy platelets and lymphocytes: Its implication in regulation

    With a view to gain an insight into the regulation of calcium activated neutral protease by its endogenous inhibitor, the inhibitor was quantitated in platelets and lymphocytes of Duchenne muscular dystrophy p...

    B. Shailaja, G. Jagadeesh, Tajamul Hussain… in Indian Journal of Clinical Biochemistry (1996)