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  1. No Access

    Article

    Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes

    Obesity, genetic polymorphisms of xenobiotic metabolic pathway, hypermethylation of tumor suppressor genes, and hypomethylation of proapoptotic genes are known to be independent risk factors for breast cancer....

    Shaik Mohammad Naushad, Tajamul Hussain… in Molecular and Cellular Biochemistry (2014)

  2. No Access

    Article

    Induction of CYP1A1, CYP1A2, CYP1B1, increased oxidative stress and inflammation in the lung and liver tissues of rats exposed to incense smoke

    Incense smoke is increasingly being recognized as a potential environmental contaminant and is linked to malignant and non-malignant respiratory diseases. The detoxification of environmental contaminants inclu...

    Tajamul Hussain, Omar S. Al-Attas… in Molecular and Cellular Biochemistry (2014)

  3. No Access

    Article

    The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects

    Paraoxonase-1 (PON1) is a HDL-bound antioxidant enzyme that protects LDL from oxidative modification. Discovery of the antioxidant properties of PON1 led to extensive research on its role in the initiation and...

    Mohammed A. Hassan, Omar S. Al-Attas… in Molecular and Cellular Biochemistry (2013)