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Open AccessInhibition of erythropoietin signalling destroys xenografts of ovarian and uterine cancers in nude mice
We have recently shown that malignant tumours from the ovary and uterus expressed erythropoietin (Epo) and its receptor (EpoR), and that deprivation of Epo signal in tumour blocks induced death of malignant ce...
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Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans
Objective: To address the clinical implications of leptin and to re-examine the relationship between leptin and its potential humoral regulators such as insulin, nonesterified fatty acids (NEFA) and triiodothyron...
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Effects of obesity phenotype on fat metabolism in obese men during endurance exercise
The effects of obesity phenotype on fat metabolism during endurance exercise are unclear. This study aimed to investigate in obese men whether body fat distribution would influence plasma fat availability and ...
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Indirect lifestyle intervention through wives improves metabolic syndrome components in men
It is well known that body weight loss through a direct (supervised) lifestyle intervention (LSI) improves obesity-related metabolic disorders. The purpose of this study was to investigate the effects of an in...
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An increase in high-density lipoprotein cholesterol after weight loss intervention is associated with long-term maintenance of reduced visceral abdominal fat
It is generally agreed that excess abdominal fat, in particular visceral abdominal fat (VAF), is related to an increased risk for obesity-related complications. We examined the association between metabolic ri...
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Long-term stable obesity increases risk of hypertension
Although some prospective cohort studies have shown that baseline BMI is positively associated with a future incident risk for hypertension, these studies do not account for weight changes during the observati...
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Multiple-slice magnetic resonance imaging can detect visceral adipose tissue reduction more accurately than single-slice imaging
Imaging methods by magnetic resonance imaging are being increasingly used to quantify visceral adipose tissue (VAT), but there is no clear consensus as to a standardized protocol. We compared the ability of tw...