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  1. No Access

    Article

    Effect of betaine onS-adenosylmethionine levels in the cerebrospinal fluid in a patient with methylenetetrahydrofolate reductase deficiency and peripheral neuropathy

    A 16-year-old Japanese girl with 5,10-methylenetetrahydrofolate reductase deficiency showed peripheral neuropathy. There were no significant responses to vitamin B6, vitamin B12 or folate, given alone or in combi...

    T. Kishi, I. Kawamura, Y. Harada, T. Eguchi… in Journal of Inherited Metabolic Disease (1994)

  2. No Access

    Article

    RB silencing compromises the DNA damage-induced G2/M checkpoint and causes deregulated expression of the ECT2 oncogene

    As alterations in retinoblastoma (RB)/E2F pathway are commonly found in human cancers, the molecular mechanism underlying cell cycle deregulation caused by the mutations in the RB/E2F pathway needs to be inves...

    T Eguchi, T Takaki, H Itadani, H Kotani in Oncogene (2007)

  3. No Access

    Article

    HSF1 regulation of β-catenin in mammary cancer cells through control of HuR/elavL1 expression

    There is now compelling evidence to indicate a place for heat shock factor 1 (HSF1) in mammary carcinogenesis, tumour progression and metastasis. Here we have investigated a role for HSF1 in regulating the exp...

    S-D Chou, A Murshid, T Eguchi, J Gong, S K Calderwood in Oncogene (2015)

  4. No Access

    Article

    Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis

    Elevated levels of the inducible heat-shock protein 70 (Hsp72) have been implicated in mammary tumorigenesis in histological investigations of human breast cancer. We therefore examined the role of Hsp72 in mi...

    J Gong, D Weng, T Eguchi, A Murshid, M Y Sherman, B Song, S K Calderwood in Oncogene (2015)