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    Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2

    The X-ray structure at 2.0-Å resolution of the p90 ribosomal S6 kinase 2 C-terminal kinase domain revealed a C-terminal autoinhibitory αL-helix that was embedded in the kinase scaffold and determines the inact...

    Margarita Malakhova, Valentina Tereshko… in Nature Structural & Molecular Biology (2008)