54 Result(s)
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Soumya Swaminathan
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Open AccessTracking global resources and capacity for health research: time to reassess strategies and investment decisions
The COVID-19 pandemic and more recently the Monkeypox outbreak emphasize the urgency and importance of improving the availability and equitable distribution of resources for health research across rich and poo...
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Open AccessA mentored hands-on training model for scaling up implementation and intervention research in India: “connecting the dots”
Despite the high burden of mental disorders in low- and middle-income countries (LMICs), less than 25% of those in need have access to appropriate services, in part due to a scarcity of locally relevant, evide...
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Transforming tuberculosis diagnosis
Diagnosis is the weakest aspect of tuberculosis (TB) care and control. We describe seven critical transitions that can close the massive TB diagnostic gap and enable TB programmes worldwide to recover from the...
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Priorities for cancer research in low- and middle-income countries: a global perspective
Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional disc...
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Open AccessPlasma chemokines as immune biomarkers for diagnosis of pediatric tuberculosis
Diagnosing tuberculosis (TB) in children is challenging due to paucibacillary disease, and lack of ability for microbiologic confirmation. Hence, we measured the plasma chemokines as biomarkers for diagnosis o...
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Open AccessThe value and promise of embedded research
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Author Correction: Patients could share virtual medical appointments for better access to telemedicine
A Correction to this paper has been published: https://doi.org/10.1038/s41591-021-01306-9.
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Patients could share virtual medical appointments for better access to telemedicine
Shared medical appointments, whereby patients with similar medical conditions consult their medical practitioner together, alleviate pressure on the health system and provide an instant support network for the...
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Open AccessIsolation and comparative genomics of Mycobacterium tuberculosis isolates from cattle and their attendants in South India
The major human pathogen Mycobacterium tuberculosis is rarely reported to cause disease in other animals. Cases in livestock are thought to occur through contact with infected handlers, but previous studies evalu...
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Tuberculosis Control: WHO Perspective and Guidelines
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Open AccessMultifocal tuberculosis-associated immune reconstitution inflammatory syndrome – a case report of a complicated scenario
Tuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretrovir...
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Open AccessAuthor Correction: Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Open AccessDifferential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome
Immune reconstitution inflammatory syndrome (IRIS) occurs in up to 40% of individuals co-infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy (ART) initiation. Phenotypic c...
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Open AccessLong-term virological outcome in children receiving first-line antiretroviral therapy
Studies relating to long-term virological outcomes among children on first-line antiretroviral therapy (ART) from low and middle-income countries are limited.
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Open AccessA randomized clinical efficacy trial of a psychosocial intervention to strengthen self-acceptance and reduce HIV risk for MSM in India: study protocol
Men who have sex with men (MSM) in India are a key group at risk for HIV acquisition and transmission. They are also an extremely marginalized and stigmatized population, facing immense psychosocial stressors ...
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Open AccessPretreatment loss to follow-up of tuberculosis patients in Chennai, India: a cohort study with implications for health systems strengthening
Pretreatment loss to follow-up (PTLFU) is a barrier to tuberculosis (TB) control in India’s Revised National TB Control Programme (RNTCP). PTLFU studies have not been conducted in India’s mega-cities, where pa...
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Open AccessHealth Technology Assessment for Policy Making in India: Current Scenario and Way Forward
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A Pilot Randomized Controlled Trial of an Integrated In-person and Mobile Phone Delivered Counseling and Text Messaging Intervention to Reduce HIV Transmission Risk among Male Sex Workers in Chennai, India
Men who have sex with men (MSM) are at increased risk for HIV infection in India, particularly those who engage in transactional sex with other men (i.e., male sex workers; MSW). Despite the need, HIV preventi...
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Open AccessA ‘Grantathon’ model to mentor new investigators in mental health research
There is a critical gap between needs and available resources for mental health treatment across the world, particularly in low- and middle-income countries (LMICs). In countries committed to increasing resour...
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Open AccessBroad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals
Broadly Cross clade Neutralizing (BCN) antibodies are recognized as potential therapeutic tools and leads for the design of a vaccine that can protect human beings against various clades of Human Immunodeficie...
