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Article
Tiny pores turning the tide
A decade ago, Zaworotko and co-workers engaged the principles of crystal engineering to demonstrate that narrow-pore (<0.7 nm) coordination networks are ideal sorbent platforms for small-molecule sorbates. Thi...
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Article
Enhanced ion mobility resolution of Abeta isomers from human brain using high-resolution demultiplexing software
Isomerization of aspartic acid (Asp) residues in long-lived proteins is a key feature associated with neurodegenerative proteinopathies such as Alzheimer’s disease (AD). Recently, using ultra high-performance ...
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Article
Insights into the beneficial roles of dark septate endophytes in plants under challenging environment: resilience to biotic and abiotic stresses
Dark septate endophytes (DSE) exert a plethora of effects in regulating plant growth, signalling and stress tolerance. The advent of metagenomics has led to the identification of various species of DSE to be a...
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Article
A decade of decoding
Molecular decoders are single host matrices able to differentiate analytes by their distinct structural accommodations. Ten years ago, Susumu Kitagawa and co-workers described the prototypical molecular decode...
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Article
Enhancement of extracellular cellobiase activity by reducing agents in the filamentous fungus Termitomyces clypeatus
Extracellular cellobiase activity of Termitomyces clypeatus increased from 2.9 U ml−1 to 4.4 and 4.1 in presence of dithiothreitol (DTT) and β-mercaptoethanol (ME), respectively, with a decrease in Km from 0.4 to...
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Article
Kinetics of serotonin oxidation by heme–Aβ relevant to Alzheimer’s disease
Serotonin (5-HT) is an essential neurotransmitter for cognitive functions and formation of new memories. A deficit in 5-HT dependent neuronal activity is somewhat specific for Alzheimer’s disease. Metal-mediat...