Skip to main content

and
  1. Article

    Open Access

    Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

    New molecular targets are needed for women with triple-negative breast cancer (TNBC). This pre-clinical study investigated the combination of the EGFR inhibitor gefitinib with the sphingosine kinase (SphK) inh...

    Janet L. Martin, Sohel M. Julovi, Mike Z. Lin in Breast Cancer Research (2017)

  2. Article

    Open Access

    Activated Protein C Inhibits Proliferation and Tumor Necrosis Factor α-Stimulated Activation of p38, c-Jun NH2-Terminal Kinase (JNK) and Akt in Rheumatoid Synovial Fibroblasts

    Synovial fibroblast proliferation Is a hallmark of the Invasive pannus in the rheumatoid joint. Activated protein C (APC) is a natural anticoagulant that exerts antiinflammatory and cyto-protective effects in ...

    Sohel M. Julovi, Kaitlin Shen, Kelly McKelvey, Nikita Minhas in Molecular Medicine (2013)

  3. No Access

    Article

    Hyaluronan inhibits IL-1β-stimulated collagenase production via down-regulation of phosphorylated p38 in SW-1353 human chondrosarcoma cells

    We investigated the intracellular mechanism for the inhibitory effects of hyaluronan (HA) on interleukin-1β (IL-1β)-stimulated collagenase-1 and -3 (matrix metalloproteinases (MMPs)-1 and -13) production in a ...

    Sohel M. Julovi, Hiromu Ito, Teruko Hiramitsu, Tadashi Yasuda in Modern Rheumatology (2008)

  4. No Access

    Article

    Requirement of mitogen-activated protein kinase for collagenase production by the fibronectin fragment in human articular chondrocytes in culture

    Fibronectin fragments have been shown to up-regulate matrix metalloproteinase production in chondrocytes. We investigated the roles of mitogen-activated protein kinase (MAPK) pathways activated by the COOH-ter...

    Tadashi Yasuda, Sohel M. Julovi, Teruko Hiramitsu, Makoto Yoshida in Modern Rheumatology (2004)