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  1. Article

    Open Access

    YOD1 protects against MRSA sepsis-induced DIC through Lys33-linked deubiquitination of NLRP3

    Disseminated intravascular coagulation (DIC) is considered to be the most common and lethal complication of sepsis. NLR-family pyrin domain-containing-3 (NLRP3) inflammasome plays an important role in host def...

    Chang Liu, Caihong Fan, Jia Liu, Shiqi Zhang, Huixin Tang in Cell Death & Disease (2024)

  2. Article

    Open Access

    Melatonin attenuates diabetic cardiomyopathy by increasing autophagy of cardiomyocytes via regulation of VEGF-B/GRP78/PERK signaling pathway

    Diabetic cardiomyopathy (DCM) is a major cause of mortality in patients with diabetes, and the potential strategies for treating DCM are insufficient. Melatonin (Mel) has been shown to attenuate DCM, however, ...

    Shengzheng Zhang, Wencong Tian, **anxian Duan, Qian Zhang in Cardiovascular Diabetology (2024)

  3. No Access

    Article

    Syringaresinol protects against diabetic nephropathy by inhibiting pyroptosis via NRF2-mediated antioxidant pathway

    Diabetic nephropathy (DN) is one of the serious complications of diabetes that has limited treatment options. As a lytic inflammatory cell death, pyroptosis plays an important role in the pathogenesis of DN. S...

    Guangru Li, Chang Liu, Lei Yang, Lifeng Feng in Cell Biology and Toxicology (2023)