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  1. Article

    Open Access

    NNMT promotes the progression of intrahepatic cholangiocarcinoma by regulating aerobic glycolysis via the EGFR-STAT3 axis

    Nicotinamide N-methyltransferase (NNMT), a member of the N-methyltransferase family, plays an important role in tumorigenesis. However, its expression and biological functions in intrahepatic cholangiocarcinom...

    Shounan Lu, Shanjia Ke, Chaoqun Wang, Yanan Xu, Zihao Li, Keda Song… in Oncogenesis (2022)

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  2. Article

    Open Access

    HLTF promotes hepatocellular carcinoma progression by enhancing SRSF1 stability and activating ERK/MAPK pathway

    Helicase-like transcription factor (HLTF) has been found to be involved in the progression of several tumors, but the role of HLTF in hepatocellular carcinoma (HCC) progression has not been studied. Here, our ...

    Yanan Xu, Shanjia Ke, Shounan Lu, Chaoqun Wang, Zihao Li, Zhigang Feng… in Oncogenesis (2023)

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  3. No Access

    Article

    RNF125 attenuates hepatocellular carcinoma progression by downregulating SRSF1-ERK pathway

    Hepatocellular carcinoma (HCC) is one of the most deadly malignant cancers worldwide. Research into the crucial genes responsible for maintaining the aggressive behaviour of cancer cells is important for the c...

    Zhigang Feng, Shanjia Ke, Chaoqun Wang, Shounan Lu, Yanan Xu, Hongjun Yu… in Oncogene (2023)