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  1. Article

    Open Access

    Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

    The phenotypes of cancer cells are driven in part by somatic structural variants. Structural variants can initiate tumors, enhance their aggressiveness, and provide unique therapeutic opportunities. Whole-geno...

    Anna Y. Lee, Adam D. Ewing, Kyle Ellrott, Yin Hu, Kathleen E. Houlahan in Genome Biology (2018)