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  1. Article

    Open Access

    Effect of Kami Guibi-tang (KGT) in elderly subjects with insomnia: a study protocol from a single center, randomized, double-blind, placebo-controlled trial

    The incidence of insomnia increases with age and is related to cognitive function in older adults; therefore, it is important to manage it actively. In this study, we report a protocol for the evaluation of th...

    Kyeong-Hwa Lee, Han-Gyul Lee, Seungwon Kwon… in BMC Complementary Medicine and Therapies (2023)

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  2. Article

    Open Access

    Effects of Kami Guibi-tang in patients with mild cognitive impairment: study protocol for a phase III, randomized, double-blind, and placebo-controlled trial

    Amnestic mild cognitive impairment (aMCI) is often considered a precursor to Alzheimer’s disease (AD) and represents a key therapeutic target for early intervention of AD. However, no treatments have been appr...

    Hee-Yeon Shin, Tae-Bin Yim, Hye-Min Heo… in BMC Complementary Medicine and Therapies (2022)

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  3. Article

    Open Access

    Efficacy and safety of Kami-guibi-tang for mild cognitive impairment: a pilot, randomized, double-blind, placebo-controlled trial

    Mild cognitive impairment (MCI) is considered an intermediate phase between normal aging and dementia. As the majority of cases of amnestic MCI (aMCI) progress to Alzheimer’s disease (AD), it is considered the...

    Hee-Yeon Shin, Ha-Ri Kim, Geon-Ho Jahng… in BMC Complementary Medicine and Therapies (2021)

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