530 Result(s)
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Article
Seong-** Yu
English
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Article
Open AccessPeroxiredoxin 1 inhibits streptozotocin-induced Alzheimer’s disease-like pathology in hippocampal neuronal cells via the blocking of Ca2+/Calpain/Cdk5-mediated mitochondrial fragmentation
Oxidative stress plays an essential role in the progression of Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced abnormal brain insulin signaling an...
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Open AccessUrine metabolomics unravel the effects of short-term dietary interventions on oxidative stress and inflammation: a randomized controlled crossover trial
Dietary biomarkers in urine remain elusive when evaluating diet-induced oxidative stress and inflammation. In our previous study, we conducted a randomized controlled crossover trial to compare the short-term ...
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A Proposal for Standardization of Early Outcomes Following Robot-Assisted Radical Cystectomy (RARC): RARC Tetrafecta
Currently, there is no dedicated tool to record the early outcomes of robot-assisted radical cystectomy (RARC), and existing criteria for longer-term outcomes require a minimum of 3 months for assessment. Howe...
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Association Between Benzene and Other Volatile Organic Compounds Exposure and Diabetes Mellitus Among Korean Adults: Findings from the Nationwide Biomonitoring Data
Volatile organic compounds (VOCs), including benzene, are environmental contaminants that are associated with various diseases. We investigated the relationship between urinary benzene metabolite, S-phenylmerc...
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Open AccessIntravitreal ranibizumab injection is associated with an increased risk of chronic kidney disease: a population-based study in Taiwan
Systemic vascular endothelial growth factor (VEGF) blockade has been the top adjunctive chemotherapy since 1990. Anti-VEGF therapy has also been associated with worsened renal function in some patients. Howeve...
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Open AccessAntitumor activity of afatinib in EGFR T790M-negative human oral cancer therapeutically targets mTOR/Mcl-1 signaling axis
This study investigates the role and effectiveness of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) in oral cancer, focusing on the clinical relevance of EGFR and myeloid cell leu...
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Open AccessChronic unpredictable stress induces autophagic death of adult hippocampal neural stem cells
Chronic psychological stress is a critical factor for neurological complications like anxiety disorders, dementia, and depression. Our previous results show that chronic restraint stress causes cognitive defic...
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Proxiome assembly of the plant nuclear pore reveals an essential hub for gene expression regulation
The nuclear pore complex (NPC) is vital for nucleocytoplasmic communication. Recent evidence emphasizes its extensive association with proteins of diverse functions, suggesting roles beyond cargo transport. Ye...
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Spatial distribution and origin of soil CO2 in Andeok area, Jeju
CO2 flux measurements and soil gas samples were collected to determine the origin and distribution characteristics of soil gas discharged at Andeok area, Jeju, South Korea. Additionally, this study aims to discus...
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Open AccessIntegrated proteomic and genomic analysis to identify predictive biomarkers for valproate response in bipolar disorder: a 6-month follow-up study
Several genetic studies have been undertaken to elucidate the intricate interplay between genetics and drug responses in bipolar disorder (BD). However, there has been notably limited research on biomarkers sp...
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Open AccessPreoperative smoking and robot-assisted radical cystectomy outcomes & complications in multicenter KORARC database
To investigate the influence of preoperative smoking history on the survival outcomes and complications in a cohort from a large multicenter database. Many patients who undergo radical cystectomy (RC) have a h...
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Open Accessp53 activation enhances the sensitivity of non-small cell lung cancer to the combination of SH003 and docetaxel by inhibiting de novo pyrimidine synthesis
Identifying molecular biomarkers for predicting responses to anti-cancer drugs can enhance treatment precision and minimize side effects. This study investigated the novel cancer-targeting mechanism of combini...
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Open AccessNomogram for predicting in-hospital mortality in trauma patients undergoing resuscitative endovascular balloon occlusion of the aorta: a retrospective multicenter study
Recently, resuscitative endovascular balloon occlusion of the aorta (REBOA) had been introduced as an innovative procedure for severe hemorrhage in the abdomen or pelvis. We aimed to investigate risk factors a...
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Open AccessDPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson’s disease
Epidemiological studies report an elevated risk of Parkinson's disease (PD) in patients with type 2 diabetes mellitus (T2DM) that is mitigated in those prescribed dipeptidyl peptidase 4 (DPP-4) inhibitors. Wit...
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Open AccessCentral neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression
We explored the genomic events underlying central neurocytoma (CN), a rare neoplasm of the central nervous system, via multiomics approaches, including whole-exome sequencing, bulk and single-nuclei RNA sequen...
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Interpersonal sensitivity and childhood trauma in patients with major depressive disorder, bipolar I, and II disorder
Childhood trauma and interpersonal sensitivity impact the development of mood disorders. In this study, we investigate the association between childhood trauma and interpersonal sensitivity in patients with mo...
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Synthesis and photocatalytic performance of hydrothermally TiO2-coated-Sr4Al14O25:Eu2+, Dy3+ phosphor beads
The TiO2 nanoparticles were supported on as-fabricated Sr4Al14O25:Eu2+,Dy3+ long-lasting phosphor beads by hydrothermal coating for easy applications of photocatalyst such as an air purifier. Zeolite and sodium s...
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Open AccessFuture changes in the wintertime ENSO-NAO teleconnection under greenhouse warming
El Niño-Southern Oscillation (ENSO) teleconnection to the Euro-Atlantic exhibits strong subseasonal variations, as the North Atlantic Oscillation (NAO) response systematically reverses its phase from early to ...
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Open AccessSitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders
The endogenous incretins glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) possess neurotrophic, neuroprotective, and anti-neuroinflammatory actions. The dipeptidyl peptida...
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Comparison of perioperative outcomes between robot-assisted adrenalectomy and laparoscopic adrenalectomy: a propensity score matching analysis
This study aimed to evaluate and compare the perioperative outcomes of robot-assisted adrenalectomy (RAA) and laparoscopic adrenalectomy (LA) using propensity score matching. This retrospective study included ...
