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Open AccessAuthor Correction: Determining protein structures in cellular lamella at pseudo-atomic resolution by GisSPA
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Open AccessThe structural basis for light acclimation in phycobilisome light harvesting systems systems in Porphyridium purpureum
Photosynthetic organisms adapt to changing light conditions by manipulating their light harvesting complexes. Biophysical, biochemical, physiological and genetic aspects of these processes are studied extensiv...
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Article
Open AccessDetermining protein structures in cellular lamella at pseudo-atomic resolution by GisSPA
Cryo-electron tomography is a major tool used to study the structure of protein complexes in situ. However, the throughput of tilt-series image data collection is still quite low. Here, we show that GisSPA, a ...
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Article
Open AccessStructure of the Acidobacteria homodimeric reaction center bound with cytochrome c
Photosynthesis converts light energy to chemical energy to fuel life on earth. Light energy is harvested by antenna pigments and transferred to reaction centers (RCs) to drive the electron transfer (ET) reacti...
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Article
Open AccessStructural insights into PA3488-mediated inactivation of Pseudomonas aeruginosa PldA
PldA, a phospholipase D (PLD) effector, catalyzes hydrolysis of the phosphodiester bonds of glycerophospholipids—the main component of cell membranes—and assists the invasion of the opportunistic pathogen Pseudom...
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Article
Open AccessNear-atomic structure of the inner ring of the Saccharomyces cerevisiae nuclear pore complex
Nuclear pore complexes (NPCs) mediate bidirectional nucleocytoplasmic transport of substances in eukaryotic cells. However, the accurate molecular arrangement of NPCs remains enigmatic owing to their huge size...
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Article
Open AccessAntenna arrangement and energy-transfer pathways of PSI–LHCI from the moss Physcomitrella patens
Plants harvest light energy utilized for photosynthesis by light-harvesting complex I and II (LHCI and LHCII) surrounding photosystem I and II (PSI and PSII), respectively. During the evolution of green plants...
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Article
Open AccessStructural basis for energy transfer in a huge diatom PSI-FCPI supercomplex
Diatom is an important group of marine algae and contributes to around 20% of the global photosynthetic carbon fixation. Photosystem I (PSI) of diatoms is associated with a large number of fucoxanthin-chloroph...
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Article
Open AccessStructural basis for specific flagellin recognition by the NLR protein NAIP5
The nucleotide-binding domain- and leucine-rich repeat (LRR)-containing proteins (NLRs) function as intracellular immune receptors to detect the presence of pathogen- or host-derived signals. The mechanisms of...
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Open AccessCryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution
The cellular ESCRT-III (endosomal sorting complex required for transport-III) and Vps4 (vacuolar protein sorting 4) comprise a common machinery that mediates a variety of membrane remodelling events. Vps4 is e...
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Cryo-EM structure of Nma111p, a unique HtrA protease composed of two protease domains and four PDZ domains
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Structural organization of an intact phycobilisome and its association with photosystem II
Phycobilisomes (PBSs) are light-harvesting antennae that transfer energy to photosynthetic reaction centers in cyanobacteria and red algae. PBSs are supermolecular complexes composed of phycobiliproteins (PBPs...
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Cryo-EM structure of SNAP-SNARE assembly in 20S particle
N-ethylmaleimide-sensitive factor (NSF) and α soluble NSF attachment proteins (α-SNAPs) work together within a 20S particle to disassemble and recycle the SNAP receptor (SNARE) complex after intracellular memb...
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The identification of a new actin-binding region in p57
The actin-binding protein p57 is a member of mammalian coronin-like proteins. The roles of this protein in phagocytic processes conceivably depend on its interactions with F-actin. Two regions, p571-34 and p57111...
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Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts
To examine the effect of daidzin, genistin, and glycitin on the osteogenic and adipogenic differentiation of bone marrow stromal cells (MSC) and the adipogenic transdifferentiation of osteoblasts.