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Article
Open AccessAnti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase is involved in the generation of specialized pro-resolving lipid mediators that play essential roles in resolution and inflammatory responses. Here, we investigated anti-inflammatory role of Al...
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Article
Open AccessConnexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue
We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated using inducible, adipocyte-specific Cx43...
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Article
Open AccessMetabolic heterogeneity of activated beige/brite adipocytes in inguinal adipose tissue
Sustained β3 adrenergic receptor (ADRB3) activation simultaneously upregulates fatty acid synthesis and oxidation in mouse brown, beige, and white adipose tissues; however, the cellular basis of this dual regu...
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Article
Open AccessSex differences in sympathetic innervation and browning of white adipose tissue of mice
The higher prevalence of obesity-related metabolic disease in males suggests that female sex hormones provide protective mechanisms against the pathogenesis of metabolic syndrome. Because browning of white adi...
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Article
Open AccessAnti-wrinkle Effects of Water Extracts of Teas in Hairless Mouse
Tea flavonoids and polyphenols are well known for their extraordinary antioxidant activity which is considered important for anti-aging processes in animals. This study evaluated the anti-wrinkle effects of th...