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Article
Open AccessClinical implications of neoadjuvant chemotherapy in advanced endometrial cancer: a multi-center retrospective cohort study
The mainstay of endometrial cancer treatment is surgical resection of tumors and postoperative adjuvant treatment is recommended if necessary. However, there is no consensus on the management of unresectable m...
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Article
A mucin-responsive hybrid two-component system controls Bacteroides thetaiotaomicron colonization and gut homeostasis
The mammalian intestinal tract contains trillions of bacteria. However, the genetic factors that allow gut symbiotic bacteria to occupy intestinal niches remain poorly understood. Here, we identified genetic d...
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The human symbiont Bacteroides thetaiotaomicron promotes diet-induced obesity by regulating host lipid metabolism
The gut microbiome plays an important role in lipid metabolism. Consumption of a high-fat diet (HFD) alters the bacterial communities in the gut, leading to metabolic disorders. Several bacterial species have ...
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Article
Open AccessEvaluation of dose point kernel rescaling methods for nanoscale dose estimation around gold nanoparticles using Geant4 Monte Carlo simulations
The absence of proper nanoscale experimental techniques to investigate the dose-enhancing properties of gold nanoparticles (GNPs) interacting with radiation has prompted the development of various Monte Carlo ...
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Article
Open AccessRadiosensitization of Prostate Cancers In Vitro and In Vivo to Erbium-filtered Orthovoltage X-rays Using Actively Targeted Gold Nanoparticles
Theoretical investigations suggest that gold nanoparticle (GNP)-mediated radiation dose enhancement and radiosensitization can be maximized when photons interact with gold, predominantly via photoelectric abso...
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Article
The effect of low-dose dexmedetomidine on hemodynamics and anesthetic requirement during bis-spectral index-guided total intravenous anesthesia
The purpose of this study was to evaluate the effects of low-dose dexmedetomidine on hemodynamics and anesthetic requirements during propofol and remifentanil anesthesia for laparoscopic cholecystectomy. Thirt...
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Article
A combined liquid chromatography-triple-quadrupole mass spectrometry method for the residual detection of veterinary drugs in porcine muscle, milk, and eggs
A liquid chromatography-electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) method was developed for monitoring and detection of four different drugs, namely acetanilide, pentylenetetrazole, phenac...
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Article
Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Article
Simple extraction method requiring no cleanup procedure for the detection of minocycline residues in porcine muscle and milk using triple quadrupole liquid chromatography-tandem mass spectrometry
A versatile analytical method was developed for simple detection of minocycline residues in porcine muscle and milk using liquid chromatography-triple quadrupole tandem mass spectrometry (LC/MS/MS) with electr...
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Article
Open AccessQuantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography
X-ray fluorescence computed tomography (XFCT) is a technique that can identify, quantify and locate elements within objects by detecting x-ray fluorescence (characteristic x-rays) stimulated by an excitation s...
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Article
Clinical outcome of low-grade central osteosarcoma and role of CDK4 and MDM2 immunohistochemistry as a diagnostic adjunct
Low-grade osteosarcoma encompasses parosteal osteosarcoma (POS) and low-grade central osteosarcoma (LCOS), with LCOS more rare than POS. LCOS is also more likely to be misdiagnosed and inappropriately treated ...
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Article
Spontaneous necrosis and additional tumor necrosis induced by preoperative chemotherapy for osteosarcoma: a case–control study
Extent of spontaneous necrosis in untreated osteosarcoma may imply tumor aggressiveness. Reports regarding this issue are scarce and there are several points to be clarified; (1) the correlation between tumor ...
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Article
A Microsurgical Suture Technique Without the Need for Vascular Clamps
Vascular clamps are often used during microvascular repair and anastomosis. However, pressure exerted by the clamps may damage the vessels, which compromises patency of vessels. This article reports on a micro...
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Article
A split-face, evaluator-blind randomized study on the early effects of Q-switched Nd:YAG laser plus Er:YAG micropeel (combined therapy) versus Q-switched Nd:YAG alone in light solar lentigines in Asians
Solar lentigines are a common sign of aging in Asians, who often asked for treatment. Various lasers, including Q-switched Nd:YAG and Er:YAG, have been adopted, but the results are not always satisfactory, esp...
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Article
Classification of Distal Fingertip Amputation Based on the Arterial System for Replantation
During replantation of distal fingertip amputation, identification of the artery is the most important but time consuming procedure. Depending on the damaged arterial structure, we classified distal fingertip ...
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Article
Agar-based heat-sensitive gel with linear thermal response over 65–80 °C
A nontoxic heat-sensitive gel containing 1.5 % (w/v) agar and 25 % (w/v) bovine serum albumin (BSA) was fabricated in this study. Optical density measurements with 808 nm near-infrared (NIR) laser indicated th...
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Article
Kinetic and mechanism studies of the adsorption of lead onto waste cow bone powder (WCBP) surfaces
This study examines the adsorption isotherms, kinetics and mechanisms of Pb2+ sorption onto waste cow bone powder (WCBP) surfaces. The concentrations of Pb2+ in the study range from 10 to 90 mg/L. Although the so...
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Article
Potential application of sludge produced from coal mine drainage treatment for removing Zn(II) in an aqueous phase
Various analyses of physico-chemical characteristics and batch tests were conducted with the sludge obtained from a full-scale electrolysis facility for treating coal mine drainage in order to find the applica...
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Article
Portable Activity Monitoring System for Temporal Parameters of Gait Cycles
A portable and wireless activity monitoring system was developed for the estimation of temporal gait parameters. The new system was built using three-axis accelerometers to automatically detect walking steps w...
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Article
Comparison between an event-by-event Monte Carlo code, NOREC, and ETRAN for electron scaled point kernels between 20 keV and 1 MeV
An event-by-event Monte Carlo code called NOREC, a substantially improved version of the Oak Ridge electron transport code (OREC), was released in 2003, after a number of modifications to OREC. In spite of som...