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  1. Article

    Open Access

    Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy

    Endoplasmic reticulum (ER) stress is associated with diabetic nephropathy (DN), but its pathophysiological relevance and the mechanisms that compromise adaptive ER signalling in podocytes remain unknown. Here ...

    Thati Madhusudhan, Hongjie Wang, Wei Dong, Sanchita Ghosh in Nature Communications (2015)