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Open AccessTherapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells
Induced pluripotent stem (iPS) cells are the novel stem cell population induced from somatic cells. It is anticipated that iPS will be used in the expanding field of regenerative medicine. Here, we investigate...
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Article
Open AccessiPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis
Angiogenic cell therapy represents a novel strategy for ischemic diseases, but some patients show poor responses. We investigated the therapeutic potential of an induced pluripotent stem (iPS) cell sheet creat...
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Article
Open AccessGADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
Autophagy is a common physiological function in all eukaryotes. The process is induced by depletion of nutrients including amino acids. GADD34 is expressed following DNA damage, ER stresses and amino acid depr...
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Open AccessEffects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice
Growth arrest and DNA damage-inducible protein 34 (GADD34/Ppp1r15a) is a family of GADD proteins that are induced by DNA damage. GADD34 protein has been suggested to regulate inflammation or host defense syste...
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Erratum to: Recruitment of Gr1+CD11b+F4/80+Population in the Bone Marrow and Spleen by Irradiation-Induced Pulmonary Damage
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Open AccessVancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils
Inflammatory bowel disease confers an increased risk of develo** colitis-associated colon cancer (CAC). During the active colitis or develo** tumor stage, commensal bacteria show dynamic translocation. How...
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Open AccessEsophageal submucosal hematoma developed after endovascular surgery for unruptured cerebral aneurysm under general anesthesia: a case report
Esophageal submucosal hematoma is a rare complication after endovascular surgery. We report a case of an esophageal submucosal hematoma which may have been caused by rigorous cough during extubation.
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Open AccessA case of pediatric Perthes’ disease with unexplained hyperlactatemia at the time of initial surgery and anesthetic management with remimazolam for the subsequent surgery
The causes of perioperative hyperlactatemia vary, but they are generally associated with hypoperfusion. Here, we report the case of a pediatric patient who developed unexplained hyperlactatemia during anesthes...