8 Result(s)

Article

Neoadjuvant chemotherapy in pancreatic cancer: innovative, but still difficult

S Boeck, M Haas, S Ormanns, S Kruger, J T Siveke, V Heinemann in British Journal of Cancer (2014)

Article

Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer

CYFRA 21-1 serves as biomarker in several epithelial malignancies. However, its role in pancreatic cancer (PC) has not yet been investigated.

S Boeck, C Wittwer, V Heinemann, M Haas, C Kern, P Stieber… in British Journal of Cancer (2013)

Article

Phase II randomised proof-of-concept study of the urokinase inhibitor upamostat (WX-671) in combination with gemcitabine compared with gemcitabine alone in patients with non-resectable, locally advanced pancreatic cancer

To evaluate the efficacy and tolerability of the urokinase plasminogen activator (uPA) inhibitor upamostat in combination with gemcitabine in locally advanced pancreatic adenocarcinoma (LAPC).

V Heinemann, M P Ebert, R P Laubender, P Bevan, C Mala… in British Journal of Cancer (2013)

Article

EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104

We aimed to identify molecular epidermal growth factor receptor (EGFR) tissue biomarkers in pancreatic cancer (PC) patients treated with the anti-EGFR agent erlotinib within the phase 3 randomised AIO-PK0104 s...

S Boeck, A Jung, R P Laubender, J Neumann, R Egg, C Goritschan… in British Journal of Cancer (2013)

Article

Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer

New therapeutic options for metastatic pancreatic cancer are urgently needed. In pancreatic cancer, overexpression of the epidermal growth factor receptor 2 (HER2) has been reported in up to 45%. This multicen...

J Harder, G Ihorst, V Heinemann, R Hofheinz, M Moehler… in British Journal of Cancer (2012)

Article

Reply to: The definition of locally advanced pancreatic cancer

S Boeck, V Heinemann in British Journal of Cancer (2010)

Article

Chemoradiotherapy with concurrent gemcitabine and cisplatin with or without sequential chemotherapy with gemcitabine/cisplatin vs chemoradiotherapy with concurrent 5-fluorouracil in patients with locally advanced pancreatic cancer – a multi-centre randomised phase II study

No standard treatment for locally advanced pancreatic cancer (LAPC) is defined.

R Wilkowski, S Boeck, S Ostermaier, R Sauer, M Herbst… in British Journal of Cancer (2009)