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  1. Article

    Open Access

    Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor

    Structural studies of integral membrane proteins have been limited by the intrinsic conformational flexibility and the need to stabilize the proteins in solution. Stabilization by mutagenesis was very successf...

    Sébastien Igonet, Claire Raingeval, Erika Cecon, Maja Pučić-Baković… in Scientific Reports (2018)

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    Article

    Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV

    The crystal structure of the GP1–GP2 complex of the prototypical arenavirus LCMV in prefusion form sheds light on the conformational changes that the arenavirus glycoprotein undergoes to cause fusion.

    Kathryn M Hastie, Sébastien Igonet… in Nature Structural & Molecular Biology (2016)