7 Result(s)

Article

Advances and opportunities in RNA structure experimental determination and computational modeling

Beyond transferring genetic information, RNAs are molecules with diverse functions that include catalyzing biochemical reactions and regulating gene expression. Most of these activities depend on RNAs’ specifi...

**song Zhang, Yuhan Fei, Lei Sun, Qiangfeng Cliff Zhang in Nature Methods (2022)

Article

IRIS: A method for predicting in vivo RNA secondary structures using PARIS data

RNA secondary structures play a pivotal role in posttranscriptional regulation and the functions of non-coding RNAs, yet in vivo RNA secondary structures remain enigmatic. PARIS (Psoralen Analysis of RNA Interact...

Jianyu Zhou, Pan Li, Wanwen Zeng, Wenxiu Ma, Zhipeng Lu, Rui Jiang… in Quantitative Biology (2020)

Article

Prediction and differential analysis of RNA secondary structure

RNA structure is the crucial basis for RNA function in various cellular processes. Over the last decade, high throughput structure profiling (SP) experiments have brought enormous insight into RNA secondary st...

Bo Yu, Yao Lu, Qiangfeng Cliff Zhang, Lin Hou in Quantitative Biology (2020)

Article

RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function

Vertebrate early embryogenesis is initially directed by a set of maternal RNAs and proteins, yet the mechanisms controlling this program remain largely unknown. Recent transcriptome-wide studies on RNA structu...

Boyang Shi, **song Zhang, Jian Heng, **g Gong, Ting Zhang, Pan Li… in Genome Biology (2020)

Article

Advances and challenges towards the study of RNA-RNA interactions in a transcriptome-wide scale

RNA molecules play crucial roles in various biological processes. Their regulation and function are mediated by interacting with other molecules. Among them RNA-RNA interactions (RRIs) are important in many ba...

**g Gong, Yanyan Ju, Di Shao, Qiangfeng Cliff Zhang in Quantitative Biology (2018)

Article

Erratum to: Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771

Alexander Eletsky, Donald Petrey… in Journal of Structural and Functional Genom… (2012)