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Article
Open AccessMap** and functional characterization of structural variation in 1060 pig genomes
Structural variations (SVs) have significant impacts on complex phenotypes by rearranging large amounts of DNA sequence.
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Article
Open AccessGenome-wide selection signatures detection in Shanghai Holstein cattle population identified genes related to adaption, health and reproduction traits
Over several decades, a wide range of natural and artificial selection events in response to subtropical environments, intensive pasture and intensive feedlot systems have greatly changed the customary behavio...
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Article
Open AccessThe prediction of the porcine pre-microRNAs in genome-wide based on support vector machine (SVM) and homology searching
MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression by targeting mRNAs for translation repression or mRNA degradation. Although many miRNAs have been discovered and studied in...
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Article
WRKY gene family evolution in Arabidopsis thaliana
The Arabidopsis thaliana WRKY proteins are characterized by a sequence of 60 amino acids including WRKY domain. It is well established that these proteins are involved in the regulation of various physiological p...
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Article
Molecular selection and functional divergence of HIF-α proteins in vertebrates
HIF-α transcription factors, as key master regulators of oxygen homeostasis, constitute a subgroup of the large bHLH-PAS transcription factor family and have been identified in many vertebrates. Although the a...
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Article
Comparative analysis of vertebrate PEPT1 and PEPT2 genes
The plasma membrane transport proteins belong to SoLute Carrier 15 (SLC15) family and two members of this family have been characterized extensively in higher vertebrates, namely PEPT1 and PEPT2. Despite many ...
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Article
Open AccessRegression-based approach for testing the association between multi-region haplotype configuration and complex trait
It is quite common that the genetic architecture of complex traits involves many genes and their interactions. Therefore, dealing with multiple unlinked genomic regions simultaneously is desirable.