33 Result(s)
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QiShan Wang
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Open AccessMap** and functional characterization of structural variation in 1060 pig genomes
Structural variations (SVs) have significant impacts on complex phenotypes by rearranging large amounts of DNA sequence.
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Dynamics and Hamiltonian energy analysis of a novel memristor coupled Josephson junction phototub chaotic circuit
As a circuit component with memory function, memristors have significant nonlinear physical characteristics and are widely used in the study of chaotic circuits and artificial neural networks. Given the superc...
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Open AccessPig pangenome graph reveals functional features of non-reference sequences
The reliance on a solitary linear reference genome has imposed a significant constraint on our comprehensive understanding of genetic variation in animals. This constraint is particularly pronounced for non-re...
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Open AccessA compendium of genetic regulatory effects across pig tissues
The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock, which is essential for linking genetic polymorphisms...
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Open AccessHolo-omics analysis reveals the influence of gut microbiota on obesity indicators in **hua pigs
The mechanisms behind obesity are complex and multi-faceted, involving the interplay of both host genomics and gut microbiome. In recent years, research has largely focused on these factors separately, but rar...
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Open AccessIntegrated microbiome-metabolome-genome axis data of Laiwu and Lulai pigs
Excessive fat deposition can trigger metabolic diseases, and it is crucial to identify factors that can break the link between fat deposition and metabolic diseases. Healthy obese Laiwu pigs (LW) are high in fat ...
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Open AccessPyAGH: a python package to fast construct kinship matrices based on different levels of omic data
Construction of kinship matrices among individuals is an important step for both association studies and prediction studies based on different levels of omic data. Methods for constructing kinship matrices are...
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Open AccessA web tool for the global identification of pig breeds
Natural and artificial selection for more than 9000 years have led to a variety of domestic pig breeds. Accurate identification of pig breeds is important for breed conservation, sustainable breeding, pork tra...
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Open AccessAuthor Correction: PHARP: a pig haplotype reference panel for genotype imputation
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Open AccessPHARP: a pig haplotype reference panel for genotype imputation
Pigs not only function as a major meat source worldwide but also are commonly used as an animal model for studying human complex traits. A large haplotype reference panel has been used to facilitate efficient ...
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Open AccessTargeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis
Diabetic osteoporosis (DOP) is the leading complication continuously threatening the bone health of patients with diabetes. A key pathogenic factor in DOP is loss of osteocyte viability. However, the mechanism...
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Long-term impact of conventional and optimal contribution conservation methods on genetic diversity and genetic gain in local pig breeds
There are rich and vast genetic resources of indigenous pig breeds in the world. Currently, great attention is paid to either crossbreeding or conservation of these indigenous pig breeds, and insufficient atte...
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Open AccessGenome-wide selection signatures detection in Shanghai Holstein cattle population identified genes related to adaption, health and reproduction traits
Over several decades, a wide range of natural and artificial selection events in response to subtropical environments, intensive pasture and intensive feedlot systems have greatly changed the customary behavio...
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A simplest Lorenz-like chaotic circuit and its applications in secure communication and weak signal detection
This paper is devoted to introduce a simplest Lorenz-like chaotic circuit and the calculation of Hamiltonian energy function for the corresponding dimensionless Lorenz-like chaotic system, as well as its appli...
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Inflammation suppression by dexamethasone via inhibition of CD147-mediated NF-κB pathway in collagen-induced arthritis rats
Dexamethasone (Dex) exhibits broad-spectrum anti-inflammatory effects in chronic destructive rheumatoid arthritis. We present in vivo and in vitro evidence supporting the preventive effects and underlying mech...
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Application of partial least squares in exploring the genome selection signatures between populations
Natural and artificial selection have led to substantial variation in the phenotypic traits of different populations. Therefore, there is a need to develop methods that are based on cross-population comparison...
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The yellow-fruited tomato 1 (yft1) mutant has altered fruit carotenoid accumulation and reduced ethylene production as a result of a genetic lesion in ETHYLENE INSENSITIVE2
The isolated yft1 allele controls the formation of fruit color in n3122 via the regulation of response to ethylene, carot...
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Association study between gene polymorphisms in PPAR signaling pathway and porcine meat quality traits
There is increasing evidence suggesting that fatty acids biosynthesis and metabolism are regulated by peroxisome proliferator-activated receptors (PPARs), mostly through the PPAR signaling pathway at the trans...
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Open AccessComparative study of the promotion of porcine fetal fibroblast proliferation by overexpression of two transcriptional variants of SIRT6
Mammalian Sirtuin 6 (SIRT6) plays an important role in the transcriptional silencing of silent mating-type loci, telomeres, and rDNA. However, the roles of porcine SIRT6 in cell proliferation are poorly understoo...
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Open AccessThe prediction of the porcine pre-microRNAs in genome-wide based on support vector machine (SVM) and homology searching
MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression by targeting mRNAs for translation repression or mRNA degradation. Although many miRNAs have been discovered and studied in...
