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  1. Article

    Author Correction: Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

    In the version of this article initially published, the traces in Fig. 1j and in Fig. 1k, right, were duplicated from the corresponding traces in Fig. 1c, bottom, and Fig. 1d, bottom right. The error has been ...

    Roger Marek, **gji **, Travis D. Goode, Thomas F. Giustino in Nature Neuroscience (2018)

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    Article

    Excitatory connections between the prelimbic and infralimbic medial prefrontal cortex show a role for the prelimbic cortex in fear extinction

    We elucidated the intrinsic circuitry of the medial prefrontal cortex and its role in regulating fear extinction, using neuronal tracing and optogenetic stimulation in vitro and in vivo. We show that pyramidal...

    Roger Marek, Li Xu, Robert K. P. Sullivan, Pankaj Sah in Nature Neuroscience (2018)

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    Article

    Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

    The medial prefrontal cortex (mPFC) has been implicated in the extinction of emotional memories, including conditioned fear. We found that ventral hippocampal (vHPC) projections to the infralimbic (IL) cortex ...

    Roger Marek, **gji **, Travis D. Goode, Thomas F. Giustino in Nature Neuroscience (2018)

  4. Article

    Correction: Corrigendum: Regulating anxiety with extrasynaptic inhibition

    Nat. Neurosci. 18, 1493–1500 (2015); published online 31 August 2015; corrected after print 5 October 2015 In the version of this article initially published, the grant number for U.R. was given as R01MH80006 ...

    Paolo Botta, Lynda Demmou, Yu Kasugai, Milica Markovic, Chun Xu in Nature Neuroscience (2015)

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    Article

    Regulating anxiety with extrasynaptic inhibition

    Less is known about the role of amygdala circuits in anxiety than in acute fear responses. In this study, the authors demonstrate that aversive experience induces anxiety in mice by regulating the excitability...

    Paolo Botta, Lynda Demmou, Yu Kasugai, Milica Markovic, Chun Xu in Nature Neuroscience (2015)

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    Article

    Imagined gait modulates neuronal network dynamics in the human pedunculopontine nucleus

    The pedunculopontine nucleus (PPN) is a target for deep brain stimulation for the control of gait and postural disability, but its role in gait control is not understood. Here, using extracellular single-unit ...

    Timothy L Tattersall, Peter G Stratton, Terry J Coyne, Raymond Cook in Nature Neuroscience (2014)

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    Article

    SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala

    At glutamatergic synapses, calcium influx through NMDA receptors (NMDARs) is required for long-term potentiation (LTP); this is a proposed cellular mechanism underlying memory and learning. Here we show that i...

    E S Louise Faber, Andrew J Delaney, Pankaj Sah in Nature Neuroscience (2005)

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    Article

    Presynaptic long-term depression at a central glutamatergic synapse: a role for CaMKII

    CaMKII is a calcium-activated kinase that is abundant in neurons and has been strongly implicated in memory and learning. Here we show that low-frequency stimulation of glutamatergic afferents in hippocampal s...

    Troy W. Margrie, John A. P. Rostas, Pankaj Sah in Nature Neuroscience (1998)