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  1. Article

    Open Access

    Text-mining assisted regulatory annotation

    Decoding transcriptional regulatory networks and the genomic cis-regulatory logic implemented in their control nodes is a fundamental challenge in genome biology. High-throughput computational and experimental an...

    Stein Aerts, Maximilian Haeussler, Steven van Vooren, Obi L Griffith… in Genome Biology (2008)

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    Article

    A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes

    Tiels et al. identify a bacterial glycosidase that facilitates improved modification of N-glycans on the Pompe disease enzyme α-glucosidase.

    Petra Tiels, Ekaterina Baranova, Kathleen Piens… in Nature Biotechnology (2012)