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  1. No Access

    Article

    KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570

    Mutation of KIT receptor tyrosine kinase at residue D816 results in ligand-independent constitutive kinase activity. This mutation occurs in most patients with mastocytosis, a myeloproliferative neoplasm, and ...

    A Chaix, M-L Arcangeli, S Lopez, E Voisset, Y Yang, M Vita, S Letard… in Oncogene (2014)

  2. No Access

    Article

    Mutations and deletions of ARID1A in breast tumors

    S Cornen, J Adelaide, F Bertucci, P Finetti, A Guille, D J Birnbaum, D Birnbaum… in Oncogene (2012)

  3. No Access

    Article

    Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis

    Overexpression of the ErbB2 receptor tyrosine kinase in breast cancer contributes to tumor development and is associated with poor prognosis. However, the mechanism by which ErbB2 might contribute to metastasi...

    J Gillibert-Duplantier, B Duthey, V Sisirak, D Salaün, T Gargi, O Trédan… in Oncogene (2012)

  4. Article

    Open Access

    A refined molecular taxonomy of breast cancer

    The current histoclinical breast cancer classification is simple but imprecise. Several molecular classifications of breast cancers based on expression profiling have been proposed as alternatives. However, th...

    M Guedj, L Marisa, A de Reynies, B Orsetti, R Schiappa, F Bibeau, G MacGrogan… in Oncogene (2012)

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  5. No Access

    Article

    Gain of CBL-interacting protein, a possible alternative to CBL mutations in myeloid malignancies

    J Adélaïde, V Gelsi-Boyer, J Rocquain, N Carbuccia, D J Birnbaum, P Finetti… in Leukemia (2010)

  6. No Access

    Article

    Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases

    The t(8;16)(p11;p13) is a rare translocation involved in de novo and therapy-related myelomonocytic and monocytic acute leukemia. It fuses two genes encoding histone acetyltransferases (HATs), MYST3 located at 8p...

    A Murati, C Gervais, N Carbuccia, P Finetti, N Cervera, J Adélaïde, S Struski… in Leukemia (2009)

  7. No Access

    Article

    Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles

    Invasive ductal carcinomas (IDCs) and invasive lobular carcinomas (ILCs) are the two major pathological types of breast cancer. Epidemiological and histoclinical data suggest biological differences, but little...

    F Bertucci, B Orsetti, V Nègre, P Finetti, C Rougé, J-C Ahomadegbe, F Bibeau… in Oncogene (2008)

  8. No Access

    Article

    ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines

    Breast cancers that overexpress the ERBB2 tyrosine kinase receptor may be treated with the recombinant humanized monoclonal anti-ERBB2 antibody trastuzumab (herceptin). However, resistance to this targeted the...

    C Ginestier, J Adélaïde, A Gonçalvès, L Repellini, F Sircoulomb, A Letessier… in Oncogene (2007)

  9. No Access

    Article

    Oncogenic kinases of myeloproliferative disorders induce both protein synthesis and G1 activators

    H Lelièvre, N Cervera, P Finetti, F Delhommeau, W Vainchenker, F Bertucci… in Leukemia (2006)

  10. No Access

    Article

    Gene expression profiling of breast cell lines identifies potential new basal markers

    A better molecular characterization of breast cell lines (BCL) may help discover new markers to apply to tumour samples. We performed gene and protein expression profiling of 31 BCL using whole-genome DNA micr...

    E Charafe-Jauffret, C Ginestier, F Monville, P Finetti, J Adélaïde, N Cervera… in Oncogene (2006)