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    Article

    Does neuronal expression of GDNF effectively protect dopaminergic neurons in a rat model of Parkinson's disease?

    The transfer of the Glial cell line-derived neurotrophic factor (GDNF) gene to the central nervous system by a recombinant adenoviral vector (Ad) was studied. We constructed the adenovirus vector Ad-NSE-GDNF f...

    N A Do Thi, P Saillour, L Ferrero, T Paunio, J Mallet in Gene Therapy (2007)

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    Article

    Delivery of GDNF by an E1,E3/E4 deleted adenoviral vector and driven by a GFAP promoter prevents dopaminergic neuron degeneration in a rat model of Parkinson's disease

    A new adenoviral vector (Ad-GFAP-GDNF) (Ad=adenovirus, GFAP=glial fibrillary acidic protein, GDNF=glial cell line-derived neurotrophic factor) was constructed in which (i) the E1,E3/E4 regions of Ad5 were dele...

    N A Do Thi, P Saillour, L Ferrero, J F Dedieu, J Mallet, T Paunio in Gene Therapy (2004)