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  1. Article

    Open Access

    Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients

    A growing number of druggable targets and national initiatives for precision oncology necessitate broad genomic profiling for many cancer patients. Whole exome sequencing (WES) offers unbiased analysis of the ...

    Michael Menzel, Stephan Ossowski, Sebastian Kral, Patrick Metzger in npj Precision Oncology (2023)

  2. Article

    Open Access

    TMB and BRAF mutation status are independent predictive factors in high-risk melanoma patients with adjuvant anti-PD-1 therapy

    High tumor mutational burden (TMB) is associated with a favorable outcome in metastatic melanoma patients treated with immune checkpoint inhibitors. However, data are limited in the adjuvant setting. As BRAF m...

    Julia Eckardt, Christopher Schroeder in Journal of Cancer Research and Clinical On… (2023)