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  1. No Access

    Article

    Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients

    The human chemokine stromal cell-derived factor-1 (SDF-1) or CXCL12 is involved in several homeostatic processes and pathologies through interaction with its cognate G protein-coupled receptor CXCR4. Recent re...

    Seppe Cambier, Fabio Beretta, Noëmie Pörtner… in Cellular and Molecular Life Sciences (2023)

  2. Article

    Open Access

    Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis

    Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for PCD and to date there are no specific treatments available. Neutrophils...

    Marfa Blanter, Maaike Cockx, Liesel Wittebols… in Respiratory Research (2022)

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    Article

    Phenotypical and Functional Characterization of Neutrophils in Two Pyrin-Associated Auto-inflammatory Diseases

    Familial Mediterranean Fever (FMF) and Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis (PAAND) are clinically distinct autoinflammatory disorders caused by mutations in the pyrin-encoding gene MEFV

    Bert Malengier-Devlies, Mieke Metzemaekers, Mieke Gouwy… in Journal of Clinical Immunology (2021)