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  1. Article

    Open Access

    Transcriptomic responses to drought stress in the Patagonian southern beech Nothofagus alpina

    Deciphering the genetic architecture of drought tolerance could allow the candidate genes identification responding to water stress. In the Andean Patagonian forest, the genus Nothofagus represents an ecologicall...

    Rita Maria Lopez Laphitz, María Verónica Arana in Ecological Processes (2024)

  2. No Access

    Article

    Genomic and proteomic analysis of Tausonia pullulans reveals a key role for a GH15 glucoamylase in starch hydrolysis

    Basidiomycetous yeasts remain an almost unexplored source of enzymes with great potential in several industries. Tausonia pullulans (Tremellomycetes) is a psychrotolerant yeast with several extracellular enzymati...

    Andrea Trochine, Nicolás Bellora, Paula Nizovoy in Applied Microbiology and Biotechnology (2022)

  3. No Access

    Article

    Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth

    Triple negative breast cancer (TNBC) refers to tumors that do not express clinically significant levels of estrogen and progesterone receptors, and lack membrane overexpression or gene amplification of ErbB-2/...

    María F. Chervo, Rosalía I. Cordo Russo, Ezequiel Petrillo, Franco Izzo in Oncogene (2020)

  4. Article

    Open Access

    Spontaneous circadian rhythms in a cold-adapted natural isolate of Aureobasidium pullulans

    Circadian systems enable organisms to synchronize their physiology to daily and seasonal environmental changes relying on endogenous pacemakers that oscillate with a period close to 24 h even in the absence of...

    Diana L. Franco, Paulo Canessa, Nicolás Bellora in Scientific Reports (2017)

  5. Article

    Open Access

    Comparative genomics provides new insights into the diversity, physiology, and sexuality of the only industrially exploited tremellomycete: Phaffia rhodozyma

    The class Tremellomycete (Agaricomycotina) encompasses more than 380 fungi. Although there are a few edible Tremella spp., the only species with current biotechnological use is the astaxanthin-producing yeast Pha...

    Nicolás Bellora, Martín Moliné, Márcia David-Palma, Marco A. Coelho in BMC Genomics (2016)

  6. Article

    Open Access

    A chromatin code for alternative splicing involving a putative association between CTCF and HP1α proteins

    Alternative splicing is primarily controlled by the activity of splicing factors and by the elongation of the RNA polymerase II (RNAPII). Recent experiments have suggested a new complex network of splicing reg...

    Eneritz Agirre, Nicolás Bellora, Mariano Alló, Amadís Pagès, Paola Bertucci in BMC Biology (2015)

  7. Article

    Open Access

    Positional bias of general and tissue-specific regulatory motifs in mouse gene promoters

    The arrangement of regulatory motifs in gene promoters, or promoter architecture, is the result of mutation and selection processes that have operated over many millions of years. In mammals, tissue-specific t...

    Nicolás Bellora, Domènec Farré, M Mar Albà in BMC Genomics (2007)

  8. Article

    Open Access

    Housekee** genes tend to show reduced upstream sequence conservation

    Understanding the constraints that operate in mammalian gene promoter sequences is of key importance to understand the evolution of gene regulatory networks. The level of promoter conservation varies greatly a...

    Domènec Farré, Nicolás Bellora, Loris Mularoni, Xavier Messeguer in Genome Biology (2007)